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Fig. 3 | Chinese Neurosurgical Journal

Fig. 3

From: Aquaporin 1 overexpression may enhance glioma tumorigenesis by interacting with the transcriptional regulation networks of Foxo4, Maz, and E2F families

Fig. 3

Identification of DEGs from RNA-seq data. A PCA analysis of RNA-seq samples based on the gene expression profiles of 12,121 genes using the plotPCA function in DESeq2 package. B MA plot of RNA-seq data. Red points stand for upregulated DEGs and green points for down-regulated DEGs. C Heatmap of DEGs drawn using the heatmap.2 function in the R package gplots. D RT-qPCR validation of DEGs (n = 3, t test, ***p value < 0.001)

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