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Table 2 Comparison of perioperative results

From: The role of acute normovolemic hemodilution in reducing allogeneic blood transfusion in glioblastoma surgery: a case–control study

 

ANH (n = 25)

Non-ANH (n = 35)

P value

Length of surgery (min)

227.5 ± 73.2

252.8 ± 81.1

0.219

Estimated blood loss (mL)

388.0 ± 237.3

498.6 ± 392.7

0.181

Intraoperative fluid given

 Total (mL)

2556.0 ± 595.7

2726.6 ± 1179.3

0.466

 Crystalloid (mL)

1504.0 ± 422.5

1401.4 ± 511.3

0.414

 Colloid (mL)

864.0 ± 309.4

1008.6 ± 514.1

0.216

 Intraoperative urine output (mL)

934.0 ± 486.2

805.7 ± 516.9

0.335

Postoperative laboratory studies (day 1)

 Hemoglobin (g/dL)

12.7 ± 1.9

11.6 ± 1.6

0.021

 Platelet count (K/μL)

211.6 ± 58.4

193.2 ± 56.4

0.225

 INR

1.03 ± 0.084

1.02 ± 0.064

0.673

 PT (s)

11.9 ± 1.0

11.7 ± 0.7

0.476

 APTT (s)

24.3 ± 5.6

25.8 ± 4.7

0.284

 BUN (mmol/L)

5.3 ± 1.9

4.9 ± 1.6

0.370

 Bilirubin (mg/dL)

6.9 ± 1.8

7.3 ± 3.4

0.594

 Potassium (mmol/L)

4.13 ± 0.50

4.10 ± 0.44

0.764

 Calcium (mmol/L)

2.15 ± 0.10

2.12 ± 0.14

0.451

Complications

 Hematoma, %

1 (4%)

2 (5.7%)

0.764

 Intracranial infection, %

2 (8%)

4 (11.4%)

0.663

 Pulmonary infection, %

4 (16%)

2 (5.7%)

0.383

 Hydrocephalus

1 (4%)

2 (5.7%)

0.764

 Hospital length of stay (day)

17.5 ± 6.9

17.3 ± 6.2

0.936

Clinical outcome at discharge

 Unfavorable outcome (KPS score < 70), %

8 (32%)

10 (28.6%)

0.775

 Mortality, %

1 (4%)

1 (2.9%)

0.808

  1. Data are mean ± SD or n (%). P values were calculated by Student’s t test, Mann–Whitney U test, chi-square test, or Fisher’s exact test, as appropriate. ANH acute normovolemic hemodilution, INR international normalized ratio, PT prothrombin time, APTT activated partial thromboplastin time, BUN urea nitrogen, KPS score Karnofsky Performance Scale