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Table 1 Summary of studies on MCA aneurysms

From: Treatment of middle cerebral artery (MCA) aneurysms: a review of the literature

Study name Study period Number of patients Mean/median age SAH MCA aneurysm size Follow-up (months) Good outcome Occlusion rate (%) Recurrence rate (%)
Surgical series
 Suzuki et al. [23] 1961–1981 413 259 (97.7 %)a 0b 85.0 %
 Rinne et al. [16] 1977–1992 561 48.9 513 (91.4 %)c 2–7 mm: 141 12 62 % (GOS ≤2)
8–14 mm: 104
15–24 mm: 38
≥25 mm: 17
 Ogilvy et al. [32] 1985–1989 62 1 82.3 %
 Morgan et al. [34] 1989–2009 263 52.7 0 (0.0 %) <7 mm: 153 1.5 94.7 % (mRS ≤1)
7–14 mm: 81
15–24 mm: 26
≥25 mm: 20
 Rodriguez-Hernandez et al. [15] 1997–2010 543 55.3 282 (51.9 %) “Giant”: 30 46.8d SAH: 92.0 % 98.3 3.8
UR: 72.0 % (mRS ≤2)
 Van Dijk et al. [1] 2001–2006 105 52.3 77 (73.3 %) <6 mm: 37 56.4 80 % (mRS ≤2) 89
6–10 mm: 54
>10 mm: 25
 Choi et al. [47] 2007–2010 125 58 0 (0.0 %) <5 mm: 89 22.5 100.0 % 95.8 0
5–10 mm: 54
Endovascular series
 Suzuki et al. [41] 1990–2007 115 55.1 48 (41.7 %) <10 mm: 81 15.5 82.6 % (mRS ≤2) 46.0 10.0
11–25 mm: 22
>25 mm: 12
 Bracard et al. [37] 1992–2001 140 73 (48.0 %)e <4 mm: 37 51.6 89.3 % (GOS ≤2) 84.2 9.1
4–10 mm: 90
11–20 mm: 12
>20 mm: 13
 Mortimer et al. [49] 1996–2012 295 53.7 242 (82.0 %) <10 mm: 232 35 87.1 % (GOS ≤3) 69.4 30.5
11–24 mm: 64
≥25 mm: 4
 Kadkhodayan et al. [38] 1996–2013 292 56.5 95 (27.5 %)f 6.6 mm 24 97.1 %g 68.5 8.2
 Iijima et al. [40] 1998–2002 137 48 72 (46.8 %)h 7 mm 15 89.8 % (mRS ≤3) 77.2 20.0
 Vendrell et al. [48] 1999–2006 153 49.5 98 (64.1 %) <7 mm: 104 50 92.9 % (GOS ≤2) 64.0 27.2
7–12 mm: 59
13–24 mm: 11
≥25 mm: 0
 Doerfler et al. [50] 2001–2005 31 48.3 15 (48.4 %) <6 mm: 24 6 82.4 % 86.8 20.0
6–10 mm: 7
>10 mm: 7
 Brinjiki et al. [36] 2002–2009 36 60 6 (16.7 %) ≥3 42.9
Surgical and endovascular series
 Regli et al. [42] 1993–1997 30 45.2 0 (0.0 %) <6 mm: 18 0 E: 15
6–10 mm: 11
11–25 mm: 4 S: 100
>25 mm: 1
 Güresir et al. [35] 1999–2009 E: 59 E: – E: 38 (64.4 %) E: 7 mm 60 E: 69.5 % E: 65 E: 6.8
S: 271 S: 50.4 S: 163 (60.1 %) S: 7 mm S: 71.2 % S: 98 S: 0
 Taha et al. [39] 2001–2004 133 60.28 53 (39.8 %) 7.21 mm 26.7 SAH: E: 62 %, S: 44 % E: 57.5
UR: E: 93 %, S: 81 % S: 81.4
 Diaz et al. [30] 2005–2010 E: 50 E: 57.7 E: 10 (20.0 %) E: 7.12 mm 9.02 E: 90.0 % E: 86 E: 14
S: 34 S: 57.7 S: 9 (26.5 %) S: 6.0 mm S: 94.1 % S: 95 S: 0
 Kim et al. [4] 2008–2011 E: 30 E: 56.7 E: 3 (10.0 %) 0.25–6 E: 86.7 % E: 93
S: 78 S: 58.5 S: 9 (11.5 %) S: 93.5 % S: 92
  1. SAH subarachnoid hemorrhage, E endovascular, S surgery, UR unruptured
  2. aThe authors only reported number of ruptured cases in 265 patients with single aneurysm
  3. bOutcomes were evaluated at time of discharge
  4. cLong term follow-up for 106 patients out of 480 eligible patients (22 %)
  5. dA total of 513 patients presented with SAH, 438 were attributable to MCA aneurysms
  6. eThe authors reported 140 patients with 152 MCA aneurysm, among which 73 aneurysms ruptured (48.0 %)
  7. fThe authors reported 292 patients with 346 MCA aneurysms, among which 95 aneurysms ruptured (27.5 %)
  8. gClinical outcome was only observed at 30-day post-op
  9. hThe authors reported 137 patients with 149 MCA aneurysms, among which 72 aneurysms ruptured (48.3 %)