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Table 1 Background demographic, Pre-operative Markwalder Chronic Subdural Hematoma Grading Scale (MGS), Post-operative Glasgow Outcome Scale (GOS) and Post-operative complications

From: Steroid for chronic subdural hematoma? A prospective phase IIB pilot randomized controlled trial on the use of dexamethasone with surgical drainage for the reduction of recurrence with reoperation

 

Surgery only (control arm)

Surgery and steroid (intervention arm)

All

p value

Age

70.8

71.9

71.3

 

Female

38/126 (30.2 %)

33/122 (27.0 %)

71

 

Pre-operative plan CT brain scan findings

   

 Right

42/126 (33.3 %)

49/122 (40.2 %)

91

0.325

 Left

52/126 (41.3 %)

58/122 (47.5 %)

110

0.387

 Bilateral

32/126 (25.4 %)

15/122 (12.3 %)

47

0.013

 Thickness

20.3 mm

22 mm

21.1 mm

 

Pre-operative Markwalder Chronic Subdural Hematoma Grading Scale (MGS) upon presentation

   

 Grade I

89/126 (70.6 %)

99/122 (81.1 %)

188

0.074

 Grade II

34/126 (26.9 %)

20/122 (16.4 %)

54

0.062

 Grade III

3/126 (2.38 %)

3/122 (2.46 %)

6

0.709

 Re-drainage rate

17/126 (13.5 %)

8/122 (6.56 %)

25

0.109

Post-operative Glasgow Outcome Scale (GOS)

   

 GOS 5 (good recovery)

91/126 (72.2 %)

99/122 (81.1 %)

 

0.131

 GOS 4 (moderate disability)

14/126 (11.1 %)

5/122 (4.10 %)

 

0.066

 GOS 3 (severe disability)

16/126 (12.7 %)

15/122 (12.3 %)

 

0.924

 GOS 2 (vegetative state)

2/126 (1.59 %)

0/122 (0 %)

 

0.492

 GOS 1 (death)

3/126 (2.38 %)

3/122 (2.46 %)

 

0.709

Post-operative complications

   

 Chest infection

1/126 (0.79 %)

5/122 (4.10 %)

 

0.201

 Post-op fever

1/126 (0.79 %)

1/122 (0.82 %)

 

0.492

 UTI

1/126 (0.79 %)

0/122 (0 %)

 

0.987

 Wound infection

1/126 (0.79 %)

0/122 (0 %)

 

0.987

 Subdural empyema

0/126 (0 %)

1/122 (0.82 %)

 

0.987