Altered regional homogeneity of prefrontal cortex in Parkinson’s disease with mild cognitive impairment

Table 1 Demographic and clinical features of subjects

	HC (n = 22)	PDNC (n = 21)	PD-MCI (n = 18)	p-value
Gender (males/females)^a	16/6	16/5	14/4	0.930
Age (years)^b	61.95 ± 5.27	61.24 ± 6.41	62.83 ± 5.38	0.688
Disease duration (years)^b	NA	5.73 ± 3.27	6.62 ± 4.55	0.481
Education (years)^a	9.27 ± 2.12	10.38 ± 3.49	9.55 ± 3.63	0.435
MoCA^a	27.86 ± 1.39	27.90 ± 1.26	20.72 ± 2.42	<0.001
MMSE^a	29.59 ± 0.59	29.38 ± 0.80	27.83 ± 1.54	<0.001
UPDRS III^b	NA	17.95 ± 9.23	24.00 ± 10.98	0.070
H-Y Stage^a	NA	1.90 ± 0.70	2.44 ± 0.98	0.061

Date are showed as means ± standard deviations. PD Parkinson’s disease, HC healthy control, PDNC PD with normal cognition, PD-MCI PD with mild cognitive impairment, NA non available, MoCA Montreal Cognitive Assessment, MMSE Mini-Mental State Examination, UPDRS III Unified Parkinson’s Disease Rating Scale part III, H-Y Stage Hoehn-Yahr stage
^a p values were calculated using Kruskal-Wallis test;
^b p values were calculated using one-way analysis of variance

ISSN: 2057-4967