Sponsor | Start Date | Design | Brief title | Aim |
---|---|---|---|---|
Charite University, Berlin, Germany | December 2010 | Single blind, Randomized | EARLYdrain - Outcome After Early Lumbar CSF-drainage in Aneurysmal SAH | To investigate whether drainage of cerebral spinal fluid via a lumbar route will improve outcome after intracranial SAH |
University of Erlangen-Nürnberg Medical School | June 2010 | Open label, Randomized | A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage | To determine if usage of early lumbar drainage leads to less shunt surgery and less catheter associated complications in patients with communicating hydrocephalus after intracerebral hemorrhage with severe ventricular involvement |
Odense University Hospital | August 2013 | Open label, Randomized | Use of Lumbar Drain to Remove Clots in Patients Admitted to the Neuro-ICU After Subarachnoid Hemorrhage | To test if CSF obtained from ELD has a higher concentration of blood than CSF from external ventricular drain in patients suffering from SAH |
University of British Columbia | March 2008 | Single blind, Non-Randomized | Cerebrospinal Fluid (CSF) Drainage and Cytokine Profiling in the Treatment of Acute Spinal Cord Injury (SCI) | To evaluate CSF drainage as a potential neuroprotective strategy after acute spinal cord injury |
St. Joseph’s Hospital and Medical Center, Phoenix | October 2, 2015 | Open label, Randomized | Cerebrospinal Fluid Drainage (CSFD) in Acute Spinal Cord Injury | To evaluate the safety and efficacy of CSFD and to provide a preliminary clinical efficacy evaluation of the combination of CSFD and elevation of mean arterial pressure in patients with acute spinal cord injury |