CSF S100B in patients treated by endovascular coiling or surgical clipping after aneurysmal subarachnoid hemorrhage and its correlation to cerebral vasospasm

Table 1 Characteristics of patients with CVS compared to patients without

Characteristic	Cerebral vasospasm (n = 19)	No cerebral vasospasm (n = 32)	P Value
Age(mean ± SD)	56.8 ± 10.4	58.0 ± 11.9	0.721^a
Gender
Male	9	18	0.705^b
Female	10	14
GCS at admission (mean ± SD)	7.16 ± 1.95	6.34 ± 1.47	0.098^a
WFNS grade
I	0	6	0.257^b
II	2	8
III	5	12
IV	8	5
V	4	1
Treatment
Surgical clipping	12	15	0.202^b
Endovascular coiling	7	17
CSF S100B level (μg/L) (mean ± SD)
Day 2–4	16.5 ± 4.97	12.2 ± 3.63	7.11 × 10^-4a
Day 6	19.58 ± 11.59	10.23 ± 3.17	7.42 × 10^-5a
Day 8	19.28 ± 13.94	8.49 ± 2.78	9.0 × 10^-5a
Day 10	16.99 ± 14.07	6.45 ± 2.48	1.29 × 10^-4a
Day 12	14.76 ± 13.94	4.34 ± 2.19	1.23 × 10^-4a
Mean	17.43 ± 11.34	8.33 ± 2.81	7.04 × 10^-5a

Abbreviations: CVS cerebral vasospasm, WFNS World federation of neurological societies grading scale, GCS Glasgow coma scale, CSF cerebrospinal fluid, SD standard deviation
^aStudent’s t test
^bFisher’s exact test

ISSN: 2057-4967