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Table 1 Patients’ characteristics and incidence of BM according to risk factors

From: Risk factors and treatments for brain metastasis in patients with adenocarcinoma of the lung: a retrospective analysis of 373 patients

Variables No. % No. of BM Incidence of BM(%) P value
Gender      0.33
 Male 209 56 104 49.8  
 Female 164 44 87 53.0  
Age      0.007
  ≤ 60 200 53.6 120 60.0  
  > 60 173 46.4 71 41.0  
Stage      0.001
 I/II 78 26.4 26 33.3  
 III/IV 295 73.6 165 55.9  
T status      0.67
 T1-2 251 67.3 131 52.2  
 T3-4 122 32.7 60 49.2  
N status      0.024
 N0-1 159 42.6 67 42.1  
 N2-3 214 57.4 124 57.9  
EGFR status(N = 100)      0.48
 Wild-type 49 49.0 22 44.9  
 Mutation 51 51.0 20 39.2  
Histology      < 0.001
 Adenocarcinoma 345 92.5 184 53.3  
 Non-adenocarcinoma 28 7.5 7 25.0  
Smoking status      0.39
 Never 239 64.1 124 55.6  
 Current 134 35.9 67 50.0  
  1. Abbreviations: BM brain metatasis, EGFR epidermal growth factor receptor, BAC Bronchioloalveolar carcinoma