Risk factors and treatments for brain metastasis in patients with adenocarcinoma of the lung: a retrospective analysis of 373 patients

Table 1 Patients’ characteristics and incidence of BM according to risk factors

Variables	No.	%	No. of BM	Incidence of BM(%)	P value
Gender					0.33
Male	209	56	104	49.8
Female	164	44	87	53.0
Age					0.007
≤ 60	200	53.6	120	60.0
> 60	173	46.4	71	41.0
Stage					0.001
I/II	78	26.4	26	33.3
III/IV	295	73.6	165	55.9
T status					0.67
T1-2	251	67.3	131	52.2
T3-4	122	32.7	60	49.2
N status					0.024
N0-1	159	42.6	67	42.1
N2-3	214	57.4	124	57.9
EGFR status(N = 100)					0.48
Wild-type	49	49.0	22	44.9
Mutation	51	51.0	20	39.2
Histology					< 0.001
Adenocarcinoma	345	92.5	184	53.3
Non-adenocarcinoma	28	7.5	7	25.0
Smoking status					0.39
Never	239	64.1	124	55.6
Current	134	35.9	67	50.0

Abbreviations: BM brain metatasis, EGFR epidermal growth factor receptor, BAC Bronchioloalveolar carcinoma

ISSN: 2057-4967