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Table 3 Characteristics of patients with BM

From: Risk factors and treatments for brain metastasis in patients with adenocarcinoma of the lung: a retrospective analysis of 373 patients

Variables No. %
Number of BM
 1 97 50.8
 2-3 39 20.4
  > 3 55 28.8
Presence of systemic metastasis at the time of BM
 Yes 161 84.3
 No 30 15.7
Treatments after BM
 None 14 7.3
 Local therapy only 63 33.0
 Local+systemic therapy 98 51.3
 systemic therapy only 16 8.4
Local therapy (n = 161)
 SRS 105(9)a 65.2
 WBRT 40(1) 24.8
 SRS + WBRT 16(2) 10.0
Systemic therapy regimens(n = 114)
 Third-generation regimens 20 17.5
 Pemetrexed 19 16.7
 TKIs 37 32.5
 Third-generation+pemetrexed 4 3.5
 Third-generation+TKIs 19 16.7
 Pemetrexed+TKIs 15 13.1
  1. Abbreviations: BM brain metatasis, RPA Recursive partitioning analysis, GPA graded prognostic assessment, WBRT whole brain radiation therapy, SRS stereotactic radiosurgery, TKIs tyrosine kinase inhibitors
  2. aNumber in the blanket was number of patients who received surgery for brain lesions