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Table 1 Curacao criteria for the diagnosis of HHT

From: Severe cerebral abscess associated with pulmonary arteriovenous fistula: case report and literature review

1. Epistaxis—spontaneous, recurrent nosebleeds
2. Telangiectases—multiple, at characteristic sites (lips, oral cavity, fingers, nose)
3. Visceral lesions—such as gastrointestinal telangiectasia (with or without bleeding), pulmonary arteriovenous fistula (AVF), hepatic AVF, cerebral AVF, spinal AVF
4. Family history—a first-degree relative with HHT
  1. The third criterion indicates a definite diagnosis of HHT
  2. The second criterion indicates a possible or suspected HHT