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Table 2 Differential proteins identified in urine samples before and after tumor resection in glioma patients

From: Urinary biomarker discovery in gliomas using mass spectrometry-based clinical proteomics

Uniprot

Description

FCa

P

Refb

P35443

Thrombospondin-4 (TSP4)#

↓ 13.0

0.024

 

P61604

10 kDa heat shock protein, mitochondrial (CH10)#

↑ 8.5

0.018

 

Q8IZF2

Adhesion G protein-coupled receptor F5 (AGRF5)#

↑ 7.0

0.018

 

P20073

Annexin A7 (ANXA7)

↑ 6.0

0.034

[18]

P40926

Malate dehydrogenase, mitochondrial (MDHM)#

↑ 4.2

0.007

 

P02511

Alpha-crystallin B chain (CRYAB)

↑ 3.9

0.033

[19]

P09417

Dihydropteridine reductase (DHPR)

↑ 2.5

0.039

[20]

O43451

Maltase-glucoamylase, intestinal (MGA)#

↑ 2.4

0.010

 

P13489

Ribonuclease inhibitor (RINI)#

↓ 2.4

0.049

 

Q9H3G5

Probable serine carboxypeptidase (CPVL)#

↑ 2.3

0.015

 

P13473

Lysosome-associated membrane glycoprotein 2 (LAMP2)#

↑ 2.2

0.012

[21]

Q92820

Gamma-glutamyl hydrolase (GGH)

↑ 2.0

0.015

 

Q07075

Glutamyl aminopeptidase (AMPE)#

↑ 2.0

0.046

[20]

Q5ZPR3

CD276 antigen (CD276)#

↑ 1.9

0.042

[22]

O96009

Napsin-A (NAPSA)

↑ 1.9

0.005

 

Q13510

Acid ceramidase (ASAH1)#

↑ 1.9

0.001

[23]

Q9BQ51

Programmed cell death 1 ligand 2 (PD1L2)

↑ 1.9

0.004

[24, 25]

P11279

Lysosome-associated membrane glycoprotein 1 (LAMP1)#

↑ 1.8

0.028

[20]

Q13228

Selenium-binding protein 1 (SBP1)#

↑ 1.7

0.035

[26]

P42785

Lysosomal Pro-X carboxypeptidase (PCP)#

↑ 1.6

0.012

 

P08236

Beta-glucuronidase (BGLR)

↑ 1.6

0.022

[27]

P15144

Aminopeptidase N (AMPN)#

↑ 1.6

0.043

[28]

P01833

Polymeric immunoglobulin receptor (PIGR)

↑ 1.5

0.043

[29]

Q96PD5

N-acetylmuramoyl-L-alanine amidase (PGRP2) #

↓ 1.5

0.043

 

P07339

Cathepsin D (CTSD)

↑ 1.5

0.043

[30]

P13688

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)#

↑ ∞

0.052

[31]

P27797

Calreticulin (CALR)

↓ ∞

0.068

[32]

  1. #Differential urinary proteins from both proteome analyses are in bold
  2. aChange trends of proteins after tumor resection
  3. bProteins associated with gliomas in previous studies