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Table 2 Quality assessment of the included trials

From: The effect of tranexamic acid in patients with TBI: a systematic review and meta-analysis of randomized controlled trials

CriteriaDesignQuality assessment
ConcealmentIntention-to-treat analysisBlindingOutcome reporting biasQuality of evidence
Chakroun-Walha 2019 [11]Randomized trialsYesYesYesNone detectedHigh
CRASH-2 trial collaborators 2011 [10]Randomized trialsYesYesYesNone detectedHigh
CRASH-3 trial collaborators 2019 [5]Randomized trialsYesYesYesNone detectedHigh
Fakharian 2018 [12]Randomized trialsYesYesYesNone detectedHigh
Roberts 2013 [2013]Randomized trialsYesYesYesNone detectedHigh
Yutthakasemsunt 2013 [13]Randomized trialsYesYesYesNone detectedHigh