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Table 3 Comparison of clinical presentation between pituitary apoplexy cases (n = 121) and controls (n = 242)

From: Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China

Symptom/sign

Pituitary apoplexy (n = 121)

control (n = 242)

P

n

%

n

%

Headache

87

71.9

130

53.7

0.001*

Vomiting

23

19.0

14

5.80

0.000*

Fever

3

2.5

5

2.10

0.800*

Visual impairment

80

66.1

155

64.0

0.698*

Diplopia

2

1.7

7

2.90

0.474*

Ablepsia

12

10.0

11

4.50

0.045*

Visual field defect

51

50.4

124

51.20

0.882*

Acromegaly

5

4.1

18

7.40

0.223*

Cushingoid appearance

0

0

4

1.7

0.356

Sexual hypoactivityb

0

0

3

1.2

0.463

Hypopituitarism

20

16.5

28

11.6

0.189*

Hypothyroidism

32

26.45

31

12.81

0.001*

Amenorrheaa

16

15.84

72

12.57

0.542*

Altered menstrual cyclea

14

11.57

26

10.74

0.406*

Galactorrhoeaa

19

15.70

23

9.50

0.026*

Gynecomastiab

0

0

0

0

  1. *Pearson’s chi-squared test
  2. aThese calculations include only women
  3. Pearson’s statistic with a continuity correction
  4. bThese calculations include only men