Table 1 Uni- and multivariate Cox regression analysis of the risk score and clinicopathologic factors for OS in TCGA and CGGA databases

Variable

P value

HR

95% CI for HR

P value

HR

95% CI for HR

Gender

0.350

1.145

0.862-1.519

Age

<0.0001

1.073

1.061-1.084

<0.0001

1.057

1.043-1.072

IDH 1 status

<0.0001

0.163

0.121-0.219

0.085

0.726

0.504-1.045

MGMT promoter status

<0.0001

0.337

0.247-0.461

0.067

0.712

0.494-1.025

Grade

<0.0001

4.794

3.798-6.051

<0.0001

2.071

1.538-2.788

RiskScore

<0.0001

3.182

2.682-3.777

<0.0001

2.050

1.620-2.593

Variable

P value

HR

95% CI for HR

P value

HR

95% CI for HR

Gender

0.345

1.181

0.837-1.666

Age

<0.0001

1.038

1.023-1.054

0.368

1.007

0.991-1.023

IDH 1 status

<0.0001

0.256

0.178-0.368

0.165

0.687

0.405-1.167

MGMT promoter status

<0.0001

0.516

0.362-0.736

0.077

0.706

0.480-1.039

Grade

<0.0001

3.477

2.716-4.452

<0.0001

2.513

1.850-3.415

Chemotherapy

0.125

1.151

0.962-1.378

Radiotherapy

0.688

0.945

0.718-1.244

RiskScore

<0.0001

>10

>10

0.025

>10

>10