From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors
Subgroup analysis | No. of studies | No. of patients | Pool OR (95% CI) | Weight | Heterogeneity random | ||
---|---|---|---|---|---|---|---|
Fixed | Random | I2 (%) | p value | ||||
ORs of tumor stage subgroup | 9 | 639 | 3.94 [2.80, 5.53] | 3.91 [2.77, 5.51] | 100% | 0 | 0.46 |
Cancer type | |||||||
 Digestive system | 4 | 222 | 4.54 [2.58, 8.00] | 4.54 [2.58, 8.00] | 36.60% | 0 | 0.76 |
 Respiratory system | 1 | 129 | 3.79 [1.75, 8.19] | 3.79 [1.75, 8.19] | 20.00% | - | - |
 Reproductive system | 2 | 178 | 2.24 [1.19, 4.21] | 2.24 [1.19, 4.21] | 29.70% | 0 | 0.87 |
 Nervous system | 1 | 79 | 8.79 [3.17, 24.32] | 8.79 [3.17, 24.32] | 11.40% | - | - |
 Locomotor system | 1 | 31 | 10.89 [1.14, 103.98] | 10.89 [1.14, 103.98] | 2.30% | - | - |
Cut-off | |||||||
 Others | 3 |  | 3.59 [1.83, 7.02] | 3.79 [1.58, 9.07] | 25.00% | 28.5 | 0.247 |
 Median | 6 |  | 4.07 [2.74, 6.03] | 4.06 [2.73, 6.05] | 75.00% | 0 | 0.445 |
Sample size | |||||||
 Size < 60 | 4 | 235 | 3.76 [2.11, 6.69] | 3.69 [2.05, 6.62] | 34.70% | 0 | 0.48 |
 Size ≥ 60 | 5 | 404 | 4.04 [2.65, 6.14] | 4.07 [2.50, 6.65] | 65.30% | 23 | 0.46 |
Quality scores | |||||||
 Score < 80 | 4 | 269 | 2.70 [1.60, 4.54] | 2.62 [1.55, 4.44] | 42.70% | 0 | 0.6 |
 Score ≥ 80 | 5 | 370 | 5.25 [3.34, 8.26] | 5.25 [3.33, 8.28] | 57.30% | 0 | 0.73 |