Skip to main content

Table 4 The subgroup of the relationship and heterogeneity between high SNHG12 expression and lymphatic metastasis

From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors

Subgroup analysis No. of studies No. of patients Pool HR (95% CI) Weight Heterogeneity random
Fixed Random I2 (%) p value
ORs of lymphatic metastasis subgroup 5 421 2.60 [1.72, 3.91] 2.66 [1.65, 4.29] 100% 22 0.28
Cancer type
 Digestive system 2 114 5.60 [2.44, 12.89] 5.57 [2.41, 12.86] 27.70% 0 0.62
 Respiratory system 1 129 1.62 [0.76, 3.45] 1.62 [0.76, 3.45] 27.80% - -
 Reproductive system 2 178 2.29 [1.23, 4.26] 2.29 [1.23, 4.26] 44.50% 0 0.92
Cut-off
 Others 2 130 3.38 [1.60, 7.15] 3.65 [1.16, 11.44] 31.70% 51 0.15
 Median 3 291 2.31 [1.41, 3.78] 2.35 [1.35, 4.10] 68.30% 22 0.28
Sample size
 Size < 60 2 156 3.29 [1.66, 6.52] 3.65 [1.25, 10.65] 36.30% 50 0.16
 Size ≥ 60 3 265 2.27 [1.36, 3.79] 2.31 [1.29, 4.14] 63.70% 19 0.29
Quality scores
 Score < 80 3 238 2.73 [1.59, 4.67] 2.73 [1.59, 4.68] 60.50% 0 0.54
 Score ≥ 80 2 183 2.42 [1.28, 4.57] 3.09 [0.72, 13.17] 39.50% 73 0.05