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Table 5 The subgroup of the relationship and heterogeneity between high SNHG12 expression and distant metastasis

From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors

Subgroup analysis

No. of studies

No. of patients

Pool HR (95% CI)

Weight

Heterogeneity random

Fixed

Random

I2 (%)

p value

ORs of distant metastasis subgroup

6

458

2.20 [1.40, 3.46]

2.23 [1.20, 4.11]

100%

38

0.15

Cancer type

 Digestive system

2

120

3.63 [1.68, 7.87]

3.64 [1.57, 8.44]

36.70%

14

0.28

 Respiratory system

1

129

1.70 [0.75, 3.85]

1.70 [0.75, 3.85]

25.00%

-

-

 Reproductive system

2

178

1.00 [0.39, 2.54]

1.00 [0.39, 2.56]

29.00%

0

0.63

 Locomotor system

1

31

8.00 [1.33, 48.18]

8.00 [1.33, 48.18]

9.30%

-

-

Cut-off

 Others

2

107

2.43 [0.90, 6.55]

2.82 [0.46, 17.38]

24.50%

64

0.1

 Median

4

351

2.14 [1.29, 3.57]

2.14 [1.05, 4.37]

75.50%

43

0.15

Sample size

 Size < 60

2

133

1.97 [0.72, 5.33]

2.32 [0.24, 22.63]

23.10%

75

0.04

 Size ≥ 60

4

325

2.27 [1.36, 3.77]

2.28 [1.25, 4.15]

76.90%

38

0.15

Quality scores

 Score < 80

4

269

2.47 [0.83, 7.30]

2.49 [1.32, 4.69]

48.30%

60

0.06

 Score ≥ 80

2

189

1.93 [1.00, 3.70]

1.93 [1.01, 3.70]

51.70%

0

0.61