Table 6 The subgroup of the relationship and heterogeneity between high SNHG12 expression and tumor size
From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors
Subgroup analysis | No. of studies | No. of patients | Pool OR (95% CI) | Weight | Heterogeneity random | ||
|---|---|---|---|---|---|---|---|
Fixed | Random | I2 (%) | p value | ||||
ORs of tumor size subgroup | 8 | 510 | 2.79 [1.89, 4.14] | 3.29 [1.66, 6.51] | 100% | 60 | 0.01 |
Cancer type | |||||||
 Digestive system | 4 | 222 | 5.43 [3.02, 9.76] | 5.43 [3.01, 9.79] | 52.70% | 0 | 0.8 |
 Reproductive system | 2 | 178 | 0.91 [0.40, 2.09] | 1.01 [0.30, 3.43] | 21.90% | 26 | 0.24 |
 Locomotor system | 1 | 31 | 8.80 [1.69, 45.76] | 8.80 [1.69, 45.76] | 9.60% | - | - |
 Nervous system | 1 | 79 | 1.58 [0.65, 3.84] | 1.58 [0.65, 3.84] | 15.90% | - | - |
Cut-off | |||||||
 Others | 3 | 161 | 1.96 [1.05, 3.66] | 2.82 [0.58, 13.63] | 37.90% | 79 | 0.008 |
 Median | 5 | 349 | 3.53 [2.12, 5.88] | 3.73 [1.92, 7.24] | 62.10% | 33 | 0.2 |
Sample size | |||||||
 Size < 60 | 4 | 235 | 4.89 [2.36, 10.14] | 4.92 [2.37, 10.19] | 41.30% | 0 | 0.87 |
 Size ≥ 60 | 4 | 275 | 2.18 [1.36, 3.50] | 2.52 [0.86, 7.42] | 58.70% | 78 | 0.003 |
Quality scores | |||||||
 Score < 80 | 4 | 269 | 2.13 [1.18, 3.82] | 2.83 [0.79, 10.10] | 45.40% | 71 | 0.02 |
 Score ≥ 80 | 4 | 241 | 3.51 [2.06, 5.99] | 3.83 [1.75, 8.41] | 54.60% | 49 | 0.12 |