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Table 6 The subgroup of the relationship and heterogeneity between high SNHG12 expression and tumor size

From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors

Subgroup analysis No. of studies No. of patients Pool OR (95% CI) Weight Heterogeneity random
Fixed Random I2 (%) p value
ORs of tumor size subgroup 8 510 2.79 [1.89, 4.14] 3.29 [1.66, 6.51] 100% 60 0.01
Cancer type
 Digestive system 4 222 5.43 [3.02, 9.76] 5.43 [3.01, 9.79] 52.70% 0 0.8
 Reproductive system 2 178 0.91 [0.40, 2.09] 1.01 [0.30, 3.43] 21.90% 26 0.24
 Locomotor system 1 31 8.80 [1.69, 45.76] 8.80 [1.69, 45.76] 9.60% - -
 Nervous system 1 79 1.58 [0.65, 3.84] 1.58 [0.65, 3.84] 15.90% - -
Cut-off
 Others 3 161 1.96 [1.05, 3.66] 2.82 [0.58, 13.63] 37.90% 79 0.008
 Median 5 349 3.53 [2.12, 5.88] 3.73 [1.92, 7.24] 62.10% 33 0.2
Sample size
 Size < 60 4 235 4.89 [2.36, 10.14] 4.92 [2.37, 10.19] 41.30% 0 0.87
 Size ≥ 60 4 275 2.18 [1.36, 3.50] 2.52 [0.86, 7.42] 58.70% 78 0.003
Quality scores
 Score < 80 4 269 2.13 [1.18, 3.82] 2.83 [0.79, 10.10] 45.40% 71 0.02
 Score ≥ 80 4 241 3.51 [2.06, 5.99] 3.83 [1.75, 8.41] 54.60% 49 0.12