From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors
microRNAS | Cancer type | Interaction with SNHG12 | Correlation with SNHG12 | Potential target genes | Function | References |
---|---|---|---|---|---|---|
miRNA-129 | Ovarian cancer | Direct binging | Negative | SOX4 | Cell proliferation and migration | [12] |
microRNA-195 | Prostate cancer | Direct binging | Negative | Wnt/β-catenin | Cell proliferation | [36] |
miR-218 | NSCLC | Direct binging | Negative | MMP9 E-cadherin vimentin caspase3 caspase9 slug ZEB2 | Cell proliferation, invasion, and migration | [15] |
miR-125b | Cervical cancer | Direct binging | Negative | stat3 | Cell proliferation migration and invasion | [37] |
miR-101-3p | Glioma | Direct binging | Negative | FOXP1 | Proliferation AND apoptosis | [33] |
microRNA-199a/b-5p | Gastric carcinoma | Direct binging | Negative | - | Cell proliferation | [16] |
MiR-424-5p | Cervical cancer | Direct binging | Negative | - | Cell growth and invasion | [20] |
miR-195 | Glioma | Direct binging | Negative | SOX5 TDP43 | Cell proliferation, migration, and invasion | [11] |
miR-195-5p | Osteosarcoma | Direct binging | Negative | Notch2 CCND1 CDK6 CDK4 NICD HES1 | Cell proliferation, invasion, and migration | [14] |
miR-320 | Gastric cancer | Direct binging | Negative | AKT ERK CRKL | Cell proliferation and invasion | [17] |
miR-199a/b-5p | Hepatocellular carcinoma | Direct binging | Negative | Erk1 MLK3 IκB NF-κB | Cell proliferation invasion and migration | [18] |
miR-320a | Osteosarcoma | Direct binging | Negative | MCL1 | Doxorubicin resistance | [31] |
miR-181a | NSCLC | Direct binging | Negative | MAPK Slug | Multidrug resistance | [34] |
miR-199a | Ischemic stroke | Direct binging | Negative | MCP1 IL-6 VEGFA and FGFb | Death, the inflammatory response, and promote angiogenesis | [38] |
miR-150 | Oschemic stroke | Direct binging | Negative | VEGF | Angiogenesis | [40] |
miR-199a | Cerebral ischemia | Direct binging | Negative | AMPK SIRT1 | Attenuate cerebral ischemia injury | [39] |