Skip to main content

Table 7 The relationship between microRNA and SNHG12 in the occurrence and development of cancer

From: Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors

microRNAS Cancer type Interaction with SNHG12 Correlation with SNHG12 Potential target genes Function References
miRNA-129 Ovarian cancer Direct binging Negative SOX4 Cell proliferation and migration [12]
microRNA-195 Prostate cancer Direct binging Negative Wnt/β-catenin Cell proliferation [36]
miR-218 NSCLC Direct binging Negative MMP9 E-cadherin vimentin caspase3 caspase9 slug ZEB2 Cell proliferation, invasion, and migration [15]
miR-125b Cervical cancer Direct binging Negative stat3 Cell proliferation migration and invasion [37]
miR-101-3p Glioma Direct binging Negative FOXP1 Proliferation AND apoptosis [33]
microRNA-199a/b-5p Gastric carcinoma Direct binging Negative - Cell proliferation [16]
MiR-424-5p Cervical cancer Direct binging Negative - Cell growth and invasion [20]
miR-195 Glioma Direct binging Negative SOX5 TDP43 Cell proliferation, migration, and invasion [11]
miR-195-5p Osteosarcoma Direct binging Negative Notch2 CCND1 CDK6 CDK4 NICD HES1 Cell proliferation, invasion, and migration [14]
miR-320 Gastric cancer Direct binging Negative AKT ERK CRKL Cell proliferation and invasion [17]
miR-199a/b-5p Hepatocellular carcinoma Direct binging Negative Erk1 MLK3 IκB NF-κB Cell proliferation invasion and migration [18]
miR-320a Osteosarcoma Direct binging Negative MCL1 Doxorubicin resistance [31]
miR-181a NSCLC Direct binging Negative MAPK Slug Multidrug resistance [34]
miR-199a Ischemic stroke Direct binging Negative MCP1 IL-6 VEGFA and FGFb Death, the inflammatory response, and promote angiogenesis [38]
miR-150 Oschemic stroke Direct binging Negative VEGF Angiogenesis [40]
miR-199a Cerebral ischemia Direct binging Negative AMPK SIRT1 Attenuate cerebral ischemia injury [39]