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Table 5 Factor associated unfavorable outcome (mRS 3-6) at postoperative 6 months in patients with ruptured anterior communicating artery aneurysm by binary logistic regression analysis (n = 141)

From: Surgical outcomes of patients after treatment of ruptured anterior communicating artery aneurysms: “real-world” evidence from southern Thailand

 

Univariable analysis

Multivariable analysisa

Factor

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Female

1.49 (0.68–3.25)

0.320

  

Age ≥ 60

4.17 (1.78–9.77)

0.001

  

Hypertension

3.35 (1.49–7.55)

0.004

  

Presenting symptom

    

 Headache

0.67 (0.30–1.54)

0.360

  

 Vomiting

1.31 (0.60–2.88)

0.500

  

 Alteration of consciousness

4.15 (1.66–10.38)

0.002

  

 Seizure

0.54 (0.17–1.70)

0.290

  

 Hemiparesis

2.58 (0.76–8.74)

0.130

  

 Deterioration prior surgery

2.56 (0.95–6.94)

0.065

  

HH grades 3–5

2.38 (1.06–5.35)

0.036

  

WFNS grades 3–5

2.45 (1.08–5.57)

0.033

  

Aneurysm characteristics

    

 Neck width ≥ 4 mm

0.48 (0.15–1.51)

0.210

  

 DN ratio ≥ 2

0.43 (0.20–0.96)

0.039

  

 A1 hypoplasia

7.00 (2.51–19.50)

< 0.001

8.90 (2.82–28.04)

< 0.001

 Multiple aneurysm

3.04 (0.86–10.68)

0.084

  

Pre ICH

1.03 (0.44–2.42)

0.940

  

Pre HCP

2.97 (0.53–16.49)

0.220

  

Pre IVH

15.71 (4.51–54.75)

< 0.001

19.66 (5.10–75.80)

< 0.001

Delayed surgery

1.14 (0.50–2.61)

0.760

  

Multiple clips (≥ 2)

1.71 (0.75–3.90)

0.201

  

Intraoperative rupture

0.96 (0.32–2.84)

0.940

  

Operative time ≥ 5 h

1.06 (0.41–2.74)

0.900

  

Estimated blood loss ≥ 600 mL

1.39 (0.61–3.13)

0.430

  

Complications

    

 Intracerebral hemorrhage

10.30 (1.03–102.67)

0.047

  

 Neurological worse

2.28 (0.99–5.23)

0.053

  

 Symptomatic vasospasm

2.34 (0.97–5.63)

0.057

  

 Cerebral infarction

2.96 (1.33–6.62)

0.008

3.21 (1.16–8.88)

0.025

 Infectious complications

5.28 (2.28–12.23)

< 0.001

  
  1. aValue shows only the significant values in final model of multivariable logistic regression with backward elimination (likelihood ratio) method
  2. CI, confidence interval; DN, dome-to-neck; HH, Hunt and Hess grade; mRS, modified Rankin scale; Pre ICH, preoperative intracerebral hemorrhage; Pre IVH, preoperative intraventricular hemorrhage; WFNS, World Federation Neurological Society