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Table 2 GRADE classification method

From: Expert consensus on drug treatment of chronic subdural hematoma

Quality level Current definition
 High We are very confident that the true effect lies close to that of the estimate of the effect
 Moderate We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
 Low Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
 Very low We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect
Recommendation level  
 Strong Benefits clearly outweigh risk, or vice versa
 Weak Uncertainty in the estimates of benefits and risks; benefits and risk may be closely balanced