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Table 2 The comparison of ion concentrations in different chemotherapy cycles

From: Long-term adjuvant administration of temozolomide impacts serum ions concentration in high-grade glioma

Parameters

Mean ± SD

Comparison of different cycles

P value

Mean ± SD

P value

Calcium (mmol/L)

1st: 2.35 ± 0.11

1st vs 6th

0.964

1st: 2.35 ± 0.10

0.043

6th: 2.34 ± 0.12

1st vs 12th

0.507

18th: 2.290.10

 

12th: 2.34 ± 0.10

6th vs 12th

0.354

  

Magnesium (mmol/L)

1st: 0.91 ± 0.07

1st vs 6th

0.769

1st: 0.92 ± 0.08

0.394

6th: 0.90 ± 0.07

1st vs 12th

0.846

18th: 0.91 ± 0.75

 

12th: 0.91 ± 0.07

6th vs 12th

0.871

  

Iron (μmol/L)

1st: 14.89 ± 8.72

1st vs 6th

< 0.001

1st: 17.10 ± 12.10

0.280

6th: 20.08 ± 6.12

1st vs 12th

< 0.001

18th: 17.71 ± 5.54

 

12th: 19.42 ± 7.00

6th vs 12th

0.307

  

Potassium (mmol/L)

1st: 4.38 ± 0.35

1st vs 6th

< 0.001

1st: 4.30 ± 0.36

0.049

6th: 4.19 ± 0.31

1st vs 12th

< 0.001

18th: 4.11 ± 0.32

 

12th: 4.16 ± 0.41

6th vs 12th

0.479

  

Sodium (mmol/L)

1st: 141.99 ± 2.71

1st vs 6th

0.056

1st: 141.40 ± 2.60

0.563

6th: 142.58 ± 2.59

1st vs 12th

0.487

18th: 141.79 ± 2.97

 

12th: 142.03 ± 4.17

6th vs 12th

0.029

  

Chloride (mmol/L)

1st: 104.92 ± 3.15

1st vs 6th

0.009

1st: 104.46 ± 3.23

0.253

6th: 106.05 ± 3.10

1st vs 12th

0.601

18th: 105.39 ± 2.79

 

12th: 105.27 ± 4.52

6th vs 12th

0.085

  
  1. Bold numbers represent statistical significance