| DAs | Surgery | ||||
---|---|---|---|---|---|---|
Pooled result | Number of studies | Number of patients | Pooled result | Number of studies | Number of patients | |
Total | 0.78 (0.75, 0.82) | 74 | 2659 | 0.66 (0.62, 0.71) | 81 | 4397 |
Microprolactinoma | 0.86 (0.78, 0.94) | 9 | 238 | 0.79 (0.72, 0.85) | 23 | 686 |
Macroprolactinoma | 0.77 (0.72, 0.83) | 27 | 1228 | 0.57 (0.46, 0.68) | 15 | 666 |
Giant prolactinoma | 0.62 (0.51, 0.74) | 8 | 176 | 0.35 (0.08, 0.62) | 3 | 55 |
1980–1989 | 0.74 (0.59, 0.89) | 6 | 106 | 0.63 (0.52, 0.73) | 15 | 1134 |
1990–1999 | 0.83 (0.75, 0.90) | 11 | 397 | 0.64 (0.46, 0.83) | 7 | 262 |
2000–2009 | 0.79 (0.72, 0.86) | 18 | 605 | 0.69(0.60, 0.78) | 20 | 947 |
2010–2019 | 0.77 (0.71, 0.82) | 39 | 1551 | 0.67 (0.60, 0.74) | 39 | 2054 |
Bromocriptine | 0.70 (0.60, 0.80) | 14 | 330 | NA | NA | NA |
Cabergoline | 0.83 (0.78, 0.87) | 32 | 1368 | NA | NA | NA |
Microscopic surgery | NA | NA | NA | 0.68 (0.56, 0.80) | 14 | 1043 |
Endoscopic surgery | NA | NA | NA | 0.72 (0.65, 0.79) | 29 | 1156 |