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Table 4 Meta-regressiosn analysis of the biochemical cure rate and recurrence rate of DAs and surgery

From: Are dopamine agonists still the first-choice treatment for prolactinoma in the era of endoscopy? A systematic review and meta-analysis

  Biochemical cure rate Recurrence rate
Surgery DAs Surgery DAs
Gender 0.019 0.601 0.479 NAa
Year 0.154 0.103 0.479 NAa
Age 0.065 0.495 0.999 0.313
Microprolactinoma 0.880 0.578 0.350 0.732
Macroprolactinoma 0.001 0.235 0.068 0.836
Giant prolactinoma 0.482 0.029 NAa NAa
Microscopic surgery 0.843 NAb NAa NAb
Endoscopic surgery 0.199 NAb 0.773 NAb
Bromocriptine NAb 0.024 NAb 0.248
Cabergoline NAb 0.935 NAb 0.520
  1. Das dopamine agonists, NAa not applicable, because the data was not provided by included studies or enough to be included in the meta-regression analysis. NAb not applicable, because the data was not discussed or calculated in the meta-analysis