From: Primary gliosarcoma with widespread extracranial metastases—spatiotemporal morphological variation
Operation time | Pathology | Immunohistochemistry |
---|---|---|
04 June 2018 | (Intracranial space). Malignant tumors, except for gliosarcoma | ATRX ( +), P53 (mutant), IDH1R132H ( −), Ki-67 (40% +), Oligo-2 ( +), GFAP ( +) |
19 Jan. 2019 | (Right temporal lobe mass). Glioblastoma, WHO grade V, most of the tumor cells are spindle-shaped, some are epithelioid, some are obviously atypia, and there are tumor giant cells with obvious necrosis. Combined with the medical history, it is consistent with the recurrence of gliosarcoma | GFAP(+), ATRX(+), SMA(+), EMA(+), P53(mutation), IDHR132H(-), S-10(+)0, KI-67(20%-30%) |