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Table 2 Pathological results and immunohistochemistry analysis of two operation

From: Primary gliosarcoma with widespread extracranial metastases—spatiotemporal morphological variation

Operation time

Pathology

Immunohistochemistry

04 June 2018

(Intracranial space). Malignant tumors, except for gliosarcoma

ATRX ( +), P53 (mutant), IDH1R132H ( −), Ki-67 (40% +), Oligo-2 ( +), GFAP ( +)

19 Jan. 2019

(Right temporal lobe mass). Glioblastoma, WHO grade V, most of the tumor cells are spindle-shaped, some are epithelioid, some are obviously atypia, and there are tumor giant cells with obvious necrosis. Combined with the medical history, it is consistent with the recurrence of gliosarcoma

GFAP(+), ATRX(+), SMA(+), EMA(+), P53(mutation), IDHR132H(-), S-10(+)0, KI-67(20%-30%)