Table 4 Univariate analysis of early progression of astrocytoma
From: Risk factors for early progression of diffuse low-grade glioma in adults
Variable | PFS ≤ 60 months (n = 54) | PFS > 60 months (n = 40) | χ2/Z | p-Value |
|---|---|---|---|---|
Sex, n (%) | 1.154 | 0.283 | ||
Male | 25 (46.3) | 23 (57.5) | ||
Female | 29 (53.7) | 17 (42.5) | ||
Age, years, n (%) | 0.797 | 0.372 | ||
≥ 40 | 32 (59.3) | 20 (50.0) | ||
< 40 | 22 (40.7) | 20 (50.0) | ||
Tumor location, n (%) | 11.013 | 0.001 | ||
Superfical | 36 (66.7) | 38 (95.0) | ||
Deep | 18 (33.3) | 2 (5.0) | ||
Preoperative tumor volume, cm3, n (%) | 3.871 | 0.049 | ||
≤ 30 | 34 (44.4) | 15 (37.5) | ||
> 30 | 20 (55.6) | 25 (62.5) | ||
Tumor range, n (%) | 4.489 | 0.034 | ||
Single lobe | 26 (48.1) | 28 (70.0) | ||
Multiple lobe | 28 (51.9) | 12 (30.0) | ||
EOR, n (%) | −2.824a | 0.005 | ||
100 | 16 (29.6) | 24 (60.0) | ||
90–99 | 27 (50.0) | 12 (30.0) | ||
< 90 | 11 (20.4) | 4 (10.0) | ||
Treatment after first surgery, n (%) | 3.862 | 0.277 | ||
RT alone | 8 (14.8) | 3 (7.5) | ||
Chemotherapy alone | 13 (24.1) | 6 (15.0) | ||
RT + chemotherapy | 24 (44.4) | 19 (47.5) | ||
None | 9 (16.7) | 12 (30.0) |