Skip to main content
Fig. 2 | Chinese Neurosurgical Journal

Fig. 2

From: Thrombospondin-2 promotes the proliferation and migration of glioma cells and contributes to the progression of glioma

Fig. 2

Effect of exogenous TSP2 on the migration and proliferation of glioma cells. a–c Representative images of scratch wounds of human U251 glioma cells, human U87MG glioblastoma cells, and rat C6 glioma cells after 48 h (bar: 500 μm). d–f Ratio of the unhealed area between 0 and 48 h after wounding in U251, U87MG, and C6 cells treated with or without the exogenous TSP2 protein. The group treated without the exogenous TSP2 protein was regarded as the control group. U251 cells (P < 0.001), U87MG cells (P = 0.002), and C6 cells (P = 0.001) treated with the exogenous TSP2 protein migrated faster at 48 h than those treated without the exogenous TSP2 protein. g–i In the CCK-8 assay, the optical density values at 450 nm showed that the proliferation rates of U251 (P = 0.126), U87MG (P = 0.501), and C6 (P = 0.076) cells treated with 0.72 μg/ml TSP2 protein were not significantly different from those of the corresponding cells not treated with exogenous TSP2 protein after 24, 48, or 72 h of culture (P = 0.126)

Back to article page