Table 2 Univariate COX proportional hazard regression model analysis of factors associated with the survival of IDH-wild-type GBM patients
Covariate | B | SE | Hazard ratio | 95% | CI | P value |
|---|---|---|---|---|---|---|
Age | 0.026 | 0.014 | 1.026 | 0.998 | 1.055 | 0.054 |
Gender | 0.044 | 0.163 | 1.045 | 0.760 | 1.438 | 0.785 |
Multi-tumor | ||||||
 GBM only vs GBM plus other tumors | 0.138 | 0.346 | 1.148 | 0.583 | 2.260 | 0.689 |
TERT status | ||||||
 TERT wild type vs TERT mutant | 0.489 | 0.412 | 1.631 | 0.727 | 3.658 | 0.235 |
MGMT promoter status | ||||||
 MGMT Un-methy vs MGMT Methy | 0.173 | 0.388 | 1.189 | 0.556 | 2.542 | 0.656 |
Postoperative adjuvant therapy | 0.000 | |||||
 Radiotherapy vs both | 0.271 | 0.741 | 1.312 | 0.307 | 5.600 | 0.714 |
 Chemotherapy vs Both | 3.019 | 0.806 | 20.463 | 4.220 | 99.231 | 0.000 |
 Neither vs both | 2.583 | 0.445 | 13.238 | 5.537 | 31.650 | 0.000 |