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Fig. 1 | Chinese Neurosurgical Journal

Fig. 1

From: Transcriptomic analysis: the protection of over-expression thioredoxin reductase 1 in Parkinson’s disease

Fig. 1

mRNA expression profiles in the Tg-A53T and TR1-A53T groups. A Upregulation and downregulation of mRNAs in the Tg-A53T group compared to the TR1-A53T group. B, C Scatter plot illustrating mRNA expression profiles in Tg-A53T and TR1-A53T. Red represents upregulated genes and green represents downregulated genes. Black represents genes with no significant difference in expression. D Heat map and hierarchical clustering show the global expression of mRNA in Tg-A53T compared to the TR1-A53T group. Red and blue indicate high and low relative expressions, respectively. Tg-A53T (C57BL/6 mice transferred with mutant human a-syn); TR1-A53T (A53T mice injected with lentivirus-TR1 2 µl in substantia nigra pars compacta (SNc) on each side with minipump). Mice are fed for 10 months

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Chinese Neurosurgical Journal

ISSN: 2057-4967

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