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Fig. 3 | Chinese Neurosurgical Journal

Fig. 3

From: Transcriptomic analysis: the protection of over-expression thioredoxin reductase 1 in Parkinson’s disease

Fig. 3

Overexpression of TR1 decreases the expression of interleukin (IL)-7, IL-15, and cytokines in Tg-A53T than that in the TR1-A53T group. A, B KEGG pathway analysis of cytokine expression in the Tg-A53T and TR1-A53T groups. B Enlargement in A. C, D KEGG pathway analysis the expression of interleukin (IL)-15 in Tg-A53T and TR1-A53T groups. D Enlargement in C. E, F KEGG pathway analysis of the expression of IL-7 in the Tg-A53T and TR1-A53T groups. F The enlargement in E. G mRNA expression of IL-7 in control, MPP+, MPP+-LV, and MPP+-TR1 groups. Control (N2a cells cultivated with DMEM); MPP+ (N2a cells used MPP+(1 mM) for 48 h), MPP+-LV (N2a cells overexpressing lentivirus for 24 h then used MPP+ (1 mM) for 48 h. MPP+-TR1 (N2a cells overexpressing lentivirus-TR1 for 24 h, followed by MPP.+ (1 mM) for 48 h

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Chinese Neurosurgical Journal

ISSN: 2057-4967

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