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  1. Primary intraventricular hemorrhage is an uncommon cause of stroke and is often associated with longstanding, uncontrolled hypertension. Reversible cerebral vasoconstriction is also an uncommon condition chara...

    Authors: Katarina Dakay, Ryan A. McTaggart, Mahesh V. Jayaraman, Shadi Yaghi and Linda C. Wendell

    Citation: Chinese Neurosurgical Journal 2018 4:11

    Content type: Case report

    Published on:

  2. There are controversies concerning the natural history of arteriovenous malformations (AVMs) in literature and it is not clear which AVMs should be treated and which should be just observed. Objective criteria...

    Authors: Athanasios K. Petridis, Maxine Dibue-Adjei, Jan F. Cornelius, Marian Preetham Suresh, Lan Li, Marcel A. Kamp, Yousef Abusabha, Bernd Turowski, Hans Jakob Steiger and Rebecca May

    Citation: Chinese Neurosurgical Journal 2018 4:13

    Content type: Research

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  3. Inflammatory responses are implicated as crucial patho-mechanisms of vascular brain malformations. Inflammation is suggested to be a key contributor to aneurysm rupture; however it is unclear whether inflammat...

    Authors: Athanasios K. Petridis, Marian P. Suresh, Jan F. Cornelius, Richard Bostelmann, Maxine Dibué-Adjei, Lan Li, Marcel A. Kamp, Hans Jakob Steiger, Bernd Turowski and Rebecca May

    Citation: Chinese Neurosurgical Journal 2018 4:10

    Content type: Research

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  4. Shunt infection (SI) is a dreaded and major complication in the management of hydrocephalus after cerebral fluid shunts. We reviewed retrospectively shunted for hydrocephalus during the last 2 years to evaluat...

    Authors: Bing Qin, Gao Chen and Jingyin Chen

    Citation: Chinese Neurosurgical Journal 2018 4:8

    Content type: Research

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  5. Risk factors and treatments for brain metastasis (BM) in patients with adenocarcinoma have not been fully profiled in previous studies because of the enrolment of patients with tumours of mixed histology. Thus...

    Authors: Bo Li, Zhaoxia Dai, Shuai Liu, Xuenan Gu, Yanwei Liu and Xiaoguang Qiu

    Citation: Chinese Neurosurgical Journal 2018 4:9

    Content type: Research

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  6. The concept of a Hybrid Angio-Surgical Suite (HASS) has emerged as a solution to the complexity of cerebrovascular surgery and the need for immediate intraoperative feedback. When to use it, what cases are sui...

    Authors: Zeguang Ren, Shuo Wang, Kaya Xu, Maxim Mokin, Yuanli Zhao, Yong Cao, Jia Wang, Hancheng Qiu, Siviero Agazzi, Harry van Loveren and Jizong Zhao

    Citation: Chinese Neurosurgical Journal 2018 4:7

    Content type: Review

    Published on:

  7. The low-profile visualized intraluminal support (LVIS) stent has become a promising endovascular option for treating intracranial aneurysms. To achieve better treatment of aneurysms using LVIS, we developed a ...

    Authors: Qianqian Zhang, Jian Liu, Yisen Zhang, Ying Zhang, Zhongbin Tian, Wenqiang Li, Junfan Chen, Xiao Mo, Yunhan Cai, Nikhil Paliwal, Hui Meng, Yang Wang, Shengzhang Wang and Xinjian Yang

    Citation: Chinese Neurosurgical Journal 2018 4:6

    Content type: Research

    Published on:

  8. The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral Sup...

    Authors: Zhouqing Chen, Xiaoou Sun, Tai Lu, Zhengyang Lu, Ming Jiang, Chongshun Zhao, Wanchun You, Yun Zhu and Zhong Wang

    Citation: Chinese Neurosurgical Journal 2018 4:4

    Content type: Research

    Published on:

  9. Though pituitary adenomas are benign tumors in most cases, a considerable fraction of PAs behave in a malignant-like manner and invade to the adjacent structures in sellar region, especially the cavernous sinu...

    Authors: Chengxian Yang, Xinjie Bao and Renzhi Wang

    Citation: Chinese Neurosurgical Journal 2018 4:2

    Content type: Review

    Published on:

  10. Spinal dumbbell-shaped epidural cavernous malformation (CM) is a rare, hypervascular entity frequently misdiagnosed for other lesions, leading to unexpected intraoperative bleeding and suboptimal resection. Ou...

    Authors: Liang Zhang, Zhifeng Zhang, Wuyang Yang, Jifeng Shang, Wenqing Jia, Jun Yang and Yulun Xu

    Citation: Chinese Neurosurgical Journal 2018 4:3

    Content type: Research

    Published on:

  11. Primary central nervous system lymphoma(PCNSL) is a rare kind of non-Hodgkin lymphoma. Rituximab combined with high-dose methotrexate, cytarabine and dexamethasone (R-MAD regimen) were reported effective for P...

    Authors: Yuchen Wu, Xuefei Sun, Jing Liu, Jun Qian, Xueyan Bai, Yuedan Chen and Yuanbo Liu

    Citation: Chinese Neurosurgical Journal 2018 4:1

    Content type: Case report

    Published on:

  12. Intracranial aneurysm is a common cerebrovascular disease, which cause wide concern by neurosurgeons. The 3D–DSA images simulated surgical path may improve the success rate of operation in bridging surgery of ...

    Authors: Jun Sun, Zhiwei Li, Chuan Lu, Xiandong Chen, Maohua Chen, Huajun Ba and Qun Lin

    Citation: Chinese Neurosurgical Journal 2017 3:41

    Content type: Research

    Published on:

  13. The carotid artery is an important blood vessel in the human body. Its ruptures caused by accidents can be lethal cases without timely treatment. Currently, successful rescue cases have rarely been reported, h...

    Authors: Nannan Gao, Yan Zhao, Litong Zhang, Wei Wu, Jianning Zhang and Xinyu Yang

    Citation: Chinese Neurosurgical Journal 2017 3:37

    Content type: Case report

    Published on:

  14. The orbit is susceptible to traumatic injuries, and surgical management of transorbital penetrating injury with foreign body retention is challenging due to the associated risks of nervous and vascular injury....

    Authors: Ying Yao, Fang Shen, Aiqin Chen, Guangyu Ying and Yongjian Zhu

    Citation: Chinese Neurosurgical Journal 2017 3:38

    Content type: Case report

    Published on:

  15. Intracranial arterial dissection is an important cause of stroke in young and middle-aged adults, but there are no domestic or globally-accepted criteria for the diagnosis and classification of intracranial ar...

    Authors: Yan-Min Wang, Yi-Sen Zhang, Bin-Bin Sui, Xin-Jian Yang and Pei-Yi Gao

    Citation: Chinese Neurosurgical Journal 2017 3:30

    Content type: Review

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  16. Different gene expression profiles are observed in intracranial aneurysm tissue. Understanding these genes and what regulates their expression will help us to understand intracranial aneurysm pathogenesis. We ...

    Authors: Jia Wang, Lanbing Yu, Dong Zhang, Shuo Wang and Jizong Zhao

    Citation: Chinese Neurosurgical Journal 2017 3:34

    Content type: Research

    Published on:

  17. Elderly patients with primary intracranial osteolytic and externally growing atypical meningiomas are rare and easy to be misdiagnosed. Recently, a patient with an atypical meningioma was treated in our depart...

    Authors: Lei Du, Yinda Tang, Hua Zhao and Xuhui Wang

    Citation: Chinese Neurosurgical Journal 2017 3:31

    Content type: Case report

    Published on:

  18. Research on the etiology and pathophysiology of fusiform aneurysm has been impeded due to the inability to collect fusiform aneurysm specimens. We aim to resolve this through the development of a novel fusifor...

    Authors: Guoquan Jiang, Zifu Li, Xiaochun Jiang, Zhenbao Li, Shanshui Xu and Xinggen Fang

    Citation: Chinese Neurosurgical Journal 2017 3:28

    Content type: Research

    Published on:

  19. While the optimal combination of whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS) and surgical resection in the treatment of brain metastases, is controversial, the addition of SRS to surgical ...

    Authors: Hamidreza Aliabadi, Arian M. Nikpour, David S. Yoo, James E. Herndon II, John H. Sampson and John P. Kirkpatrick

    Citation: Chinese Neurosurgical Journal 2017 3:29

    Content type: Research

    Published on:

  20. Glioma stem cells (GSCs) represent a subpopulation of cells within glioma that are characterized by chemotherapy resistance and tumor recurrence. GSCs are therefore important therapeutic target for glioma ther...

    Authors: Zuoxin Zhang, Junhu Zhou, Junxia Zhang, Ran Duan, Peiyu Pu and Lei Han

    Citation: Chinese Neurosurgical Journal 2017 3:25

    Content type: Research

    Published on:

  21. Aneurysmal subarachnoid hemorrhage (aSAH) is an acute neurosurgical emergency with a significant fatality rate. In addition to acute brain injury, a considerable part of patients suffering from aSAH develops s...

    Authors: Ruiyan Li, Jianlong Li, Qingbin Li, Qinghua Yuan, Minghui Chen, Yan Feng, Yongli Li, Xiaoyan Lu, Zhongfei Hao, Mingli Liu, Jinquan Cai and Chuanlu Jiang

    Citation: Chinese Neurosurgical Journal 2017 3:24

    Content type: Research

    Published on:

  22. Fourth ventricle isolated Magendie’s foramen primitive obstruction is rare. The etiology and the pathophysiology of the constitution of this obstruction in congenital cases remain elusive. We report a case of ...

    Authors: HA N’da, S Fondjo, LK Drogba, LM Konan and V Ba Zeze

    Citation: Chinese Neurosurgical Journal 2017 3:26

    Content type: Case report

    Published on:

  23. Human leukocyte antigen (HLA)-DR is a classical major histocompatibility complex (MHC) class II molecule encoded by five genes: HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4 and HLA-DRB5. The current study aimed to in...

    Authors: Xing Fan, Jingshan Liang, Zhifeng Wu, Xia Shan, Hui Qiao and Tao Jiang

    Citation: Chinese Neurosurgical Journal 2017 3:27

    Content type: Research

    Published on:

  24. Pleomorphic xanthoastrocytoma (PXA) is usually considered a relatively benign and localized entity. However, cases of PXA with anaplastic features have been reported in recent years. Anaplastic pleomorphic xan...

    Authors: Meng Zhu, Chen Zhang, Kai Zhao, Leilei Wang, Jian Sun, Yugong Feng, Weicheng Yao, Shizhu Yu, Cuiyun Sun and Xuejun Yang

    Citation: Chinese Neurosurgical Journal 2017 3:22

    Content type: Case report

    Published on:

  25. Epithelial-mesenchymal transformation(EMT) is a coordinated process in which polarized epithelial cells are induced to lose adhesion from the basement membrane and obtain the properties of mesenchymal cells, i...

    Authors: Lei Du, Jun-Hai Tang, Guo-Hao Huang, Yan Xiang and Sheng-Qing Lv

    Citation: Chinese Neurosurgical Journal 2017 3:23

    Content type: Review

    Published on:

  26. Decompressive craniectomy (DC) has been the classical management for malignant middle cerebral artery infarctions (mMCAI) in clinical practice. However, the association between DC and mMCAI remains unclear. Th...

    Authors: Long Xu, Te Lu, Xiaogang Tao, Dandan Wang, Weiming Liu, Jingsheng Li and Baiyun Liu

    Citation: Chinese Neurosurgical Journal 2017 3:19

    Content type: Research

    Published on:

  27. Pituitary adenoma (PA) is a common intracranial tumor and surgical treatment is considered to be the best treatment for most patients. The extended endoscopic endonasal approach (EEEA) has been used to treat i...

    Authors: Xiaobing Jiang, Zhen Liu, Xing Huang, Haijun Wang and Hongyang Zhao

    Citation: Chinese Neurosurgical Journal 2017 3:18

    Content type: Research

    Published on:

  28. We aim to present an unique case of inflammatory myofibroblastic tumor (IMT) of the brain parenchyma and study the clinical presentation, imagine characteristic, intraoperative findings, and histopathology fea...

    Authors: Xuejian Wang, Zhifeng Wang, Yang Chen and Ming Qian

    Citation: Chinese Neurosurgical Journal 2017 3:12

    Content type: Case report

    Published on:

  29. Mitochondrial Ca2+ uptake is a pivotal pathophysiological process for neuronal survival when subjected to ischemic insult. Mitochondrial calcium uptake 1 (MICU1) has been demonstrated as a key regulator of the mi...

    Authors: Kun Zhang, Jiajia Yan, Liang Wang, Xinying Tian, Tong Zhang, Bin Li, Wang Wang, Li Guo and Xiaoyun Liu

    Citation: Chinese Neurosurgical Journal 2017 3:13

    Content type: Research

    Published on:

  30. With the development of emergency and intensive medical technologies, the survival rate of traumatic brain injury has greatly increased. More and more patients have been converted from severe coma to alleviate...

    Authors: Long Xu, Yi Yang, Er’an Guo, Xiaogang Tao, Te Lu, Runfa Tian, Zhu Chen, Xiaoyu Xia, Qingxia Tao, Mingmei Ge, Jianghong He, Jingsheng Li and Jizong Zhao

    Citation: Chinese Neurosurgical Journal 2017 3:17

    Content type: Research

    Published on:

  31. Tuberculum sellae meningioma associated with aneurysm is extremely rare with a limited number of individual cases previously reported. Because of the complicated anatomical structure of the skull base, comorbi...

    Authors: Jiu Geng Feng, Min Jun Wei, Rong Hua Feng, Tao Hong and Chun Hui Zeng

    Citation: Chinese Neurosurgical Journal 2017 3:11

    Content type: Case report

    Published on:

  32. Pituitary stalk thickening (PST) used as an imaging diagnosis plays a major role in diagnosis and treatment of the hypothalamus and pituitary disease at an early stage. Up until now, several lines of systemati...

    Authors: Yanjiao Cai, Xuefei Shou, Zhaoyun Zhang, Hongying Ye, Yao Zhao, Yongfei Wang, Rong Xie, Shiqi Li and Yiming Li

    Citation: Chinese Neurosurgical Journal 2017 3:2

    Content type: Research

    Published on:

  33. Although technically regarded as a simple procedure, titanium mesh cranioplasty could lead to various surgical complications, including postoperative implant exposure. However, there is little data available o...

    Authors: Han-song Sheng, Fang Shen, Mao-de Wang, Jian Lin, Fen-chun Lin, Bo Yin and Nu Zhang

    Citation: Chinese Neurosurgical Journal 2017 3:8

    Content type: Case report

    Published on:

  34. Parkinsonism-hyperpyrexia syndrome (PHS) is a rare but potentially fatal condition in patients with Parkinson’s disease. Deep brain stimulation (DBS) is a widely used and efficacious treatment for advanced Par...

    Authors: Chun-Lei Han, Yan Ge, Da-Wei Meng, Jian-Guo Zhang and Fan-Gang Meng

    Citation: Chinese Neurosurgical Journal 2017 3:10

    Content type: Case report

    Published on:

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