Articles

Biomaterial applications in neural therapy and repair

The use of biomaterials, such as hydrogels, as a scaffold to deliver cells and drugs is becoming increasingly common to treat neurological conditions, including stroke. With a limited intrinsic ability to rege...

Authors: Harmanvir Ghuman and Michel Modo

Computational fluid dynamics analysis on recurrence of simple coiling intracranial aneurysms with remnant neck

Hemodynamic factors are considered to play an important role in the initiation and recurrence of cerebral aneurysms. However, hemodynamic characteristics leading to the recurrence of aneurysms is not well reco...

Authors: Xilong Yu, Gang Lu, Shengzhang Wang, Lei Huang, Liang Ge, Jun Wan, Ruoyu Di, Yeqing Jiang and Xiaolong Zhang

MicroRNAs as biomarkers in molecular diagnosis of refractory epilepsy

MicroRNA (miRNA) is a type of endogenous non-coding RNA that can regulate cell proliferation, differentiation, invasion, apoptosis and several other biological activities by specially inducing gene silencing, ...

Authors: Xiaofeng Wang, Hang Yin, Alyson M. Rich, Yuqiang Sun, Zeshi Tan, Xiaodong Luo, Ningwei Che, Minghai Wei and Jian Yin

Omentum transposition for treatment of Alzheimer disease in China

A paper was published in a Chinese medical journal that suggested that the placing of an intact vascularized omental pedicle would increase cerebral blood flow and could decelerate the development of Alzheimer...

Authors: Harry S. Goldsmith

Lab-to-clinic application of stem cell therapy for stroke

Stem cell therapy or “cell therapy” has been demonstrated to be a potent treatment intervention in animal models of acute ischemic stroke, and recently has been introduced as an experimental therapy in early p...

Authors: Mia C. Borlongan, Sonya Kong and David C. Hess

Clinical study of quality of life of traumatic brain injury patients after decompressive craniectomy and related influencing factors

Decompressive craniectomy (DC) in traumatic brain injury (TBI) patients has been subject of debate for neurosurgeons since long time. Our goal in this study is to evaluate the quality of life of these patients...

Authors: Roodrajeetsing Gopaul, Zong Dang Wei, Jun Yan, Fan Yong Gong and Shao Wen Xiao

Could cough be an intraoperative indicator for venous air embolism in deep brain stimulation surgeries?: experiences from a large case series

Deep brain stimulation (DBS) surgery is usually performed with the patients located in a half-sitting position. Therefore, complications associated with such position accompany, such as venous air embolism (VA...

Authors: Lin Shi, Chao-Cai Zhang, Jun-Ju Li, Guan-Yu Zhu, Ying-Chuan Chen and Jian-Guo Zhang

Single stage complete resection of giant dumbbell lumbar ganglioneuroma: a case report and review of the literature

Ganglioneuroma is a rare benign tumor, which is usually located in the posterior mediastinum and retroperitoneum. Occasionally, it involves the paraspinal region with intraspinal extension and becomes dumbbell...

Authors: Zuowei Wang, Xingwen Wang, Fengzeng Jian and Li Chen

The diagnosis and management of hypothalamic hamartomas in children

Hypothalamic hamartoma (HH) is a rare developmental malformation often characterized by gelastic seizures. Recent advances in treating HH have led to dramatic improvements. However, clinical protocol of HH is ...

Authors: Baocheng Wang and Jie Ma

Endoscopic anatomical study on anterior communicating artery aneurysm surgery by endonasal transphenoidal approach

Endonasal transphenoidal approach by neuroendoscopy has its own advantage, such as direct access, invasive, better visualization of the anterior communicating artery aneurysm and so on. The study is to provide...

Authors: Junwei Ma, Zhimin Wang, Niankai Zhang, Shengshan Li, Dongyi Jiang and Hanchun Chen

Nocardial brain abscess in an immunocompetent patient and review of literature

Nocardial brain abscesses are associated with significant morbidity and mortality rates. The optimal management remains unclear.

Authors: Yinian Zhang, Wei Zhu, Qiao li, Boru Hou, Yanfei Jia, Naili Wei and Yawen Pan

Subdural hemorrhages in acute lymphoblastic leukemia: case report and literature review

Acute lymphoblastic leukemia is a rare hematological malignancy. Pure subdural hemorrhages in a patient with acute lymphoblastic leukemia patient are extremely rare.

Authors: Rui Yin, Cai-Xia Qiu, Xiao-Hui Dong and Ye-Long Chen

Three-dimensional printing technology for treatment of intracranial aneurysm

The development of three-dimensional (3D) printing technology provides a new method for surgical treatment, but currently there are few reports on its application in the treatment of aneurysm. The aim of the p...

Authors: Yin Kang, Liang-Hong Yu, Tao Xu, Shu-Fa Zheng, Pei-Sen Yao, Man Liu, Yuan-Xiang Lin, Zhang-Ya Lin, Xiao-Min Fan and De-Zhi Kang

Aneurysmal isolated intracerebral hemorrhage and/or intraventricular hemorrhage without subarachnoid hemorrhage: a rare and perplexing scenario in neurosurgical practice

Ruptured aneurysms with a presentation of intracerebral hemorrhage (ICH) and/or intraventricular hemorrhage (IVH) without subarachnoid hemorrhage (SAH) are rarely reported. Issues on the clinical characteristi...

Authors: Guichen Li, Xiaobo Zhu, Yang Zhang, Jinchuan Zhao, Xianfeng Gao and Kun Hou

Low grade astrocytoma transformating primitive neuroectodermal tumour in an adult? A case report and review of literature

Supratentorial primitive neuroectodermal tumors (sPNET) are rarely occurred in adults. Only 39 cases have been reported in the past decade. The transformation from low grade to aggressive astrocytoma is well k...

Authors: Xiaofeng Wang, Yuqiang Sun, Zeshi Tan, Anlong Ji, Xu Sun, Xinyu Li, Ningwei Che, Kang Yang, Yaoling Liu, Xiaodong Luo, Guanyu Wang, Lan Luan, Minghai Wei and Jian Yin

Transient mutism following neuroendoscopy in children; report of two cases

Since the introduction of neuro-endoscopy by Walter Dandy and his colleagues in the early 1920's, several efforts has been made to improve this tool for treatment of hydrocephalus, brain tumors, arachnoid cyst...

Authors: Nima Derakhshan and Mohammad Sadegh Masoudi

Retrosigmoid-transtentorial approach for petroclival meningiomas: operative technique and clinical outcome

Petroclival meningiomas (PCMs) are technically challenging lesions. Although the standard retrosigmoid approach is one of the most effective approaches, this route may have some limitations for the tumors exte...

Authors: Zijin Zhao, Xianrui Yuan, Jian Yuan, Jun Su, Xiangyu Wang, Weixi Jiang, Zefeng Peng, Xuejun Li and Qing Liu

The cultivation of epilepsy neurosurgeons: requirements and challenges

Epilepsy surgery has been accepted as an effective treatment in drug-resistant focal epilepsy. However, the number of epilepsy neurosurgeons is not enough in China compared with the huge demand. The content of...

Authors: Kai Zhang, Jianguo Zhang, Yanshan Ma, Xiaoqiu Shao, Wenhan Hu and Baotian Zhao

Identification of OPN, TNC and E-selectin as potential recognition proteins in cerebral vasospasm after subarachnoid hemorrhage

Cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) is a serious and significant health problem in the worldwide. There are still no effective therapies for treatment of CVS in patients suffering from...

Authors: Min Jun Wei, Jiu Geng Feng, Zhi Qun Jiang, Chun Hui Zeng, Li Ping Jiang and Tao Hong

Intracranial foreign body through the sagittal sinus: case report and review of literature

To investigate therapeutic effect of surgery that removes an intracranial foreign body through the intracranial sagittal sinus with help of intraoperative navigation and intraoperative fluorescein angiography.

Authors: Roodrajeetsing Gopaul, Wen Shao Xiao, Jun Yan and Dang Zong Wei

Erratum to: Isolated intradural Rosai-Dorfman disease of the spine: report of two cases

Authors: Yu Xin, Hui Shen, Desheng Kong, Wenqing Jia, Hai Liu and Jun Yang

Laminectomy by craniotome for huge spinal extradural arachnoid cyst: a case report

Spinal extradural arachnoid cyst is extremely rare. The longest SEACs that have been reported in previous studies involved no more than 5 spinal segments. This study presents a case of SEAC diagnosed from T9 t...

Authors: Bo Jin, Ji-zong Zhao, Han-bin Wang, Ke-da Wang, Long-qi Liu and Yi-bing Su

Some cool considerations of external lumbar drainage during its widespread application in neurosurgical practice: a long way to go

External lumbar drainage (ELD) has gained wide popularity in neurosurgical practice since its’ first introduction by F. Vourc’h in 1963. It manifests encouraging prospects in control of refractory intracranial...

Authors: Guichen Li, Yang Zhang, Jinchuan Zhao, Zhiguo Han, Xiaobo Zhu and Kun Hou

Isolated intradural Rosai-Dorfman disease of the spine: report of two cases

Rosai-Dorfman disease (RDD) is an idiopathic histiocytic proliferative disorder characterized by sinus histiocytosis and massive lymphadenopathy. Extranodal and central nervous system (CNS) involvement is unus...

Authors: Yu Xin, Hui Shen, Desheng Kong, Wenqing Jia, Hai Liu and Jun Yang

Giant colloid cyst of the third ventricle: challenges in management

Giant colloid cysts (size > 3 cm) are very rare with only few reported cases in the literature.

Authors: Amit Agrawal, Vissa Santhi and Reddy V. Umamaheswara

Plasticity of motor function and surgical outcomes in patients with cerebral arteriovenous malformation involving primary motor area: insight from fMRI and DTI

Patients who have a cerebral arteriovenous malformation (cAVMs) in the motor cortex can have displaced function. The finding and its relationship to recovery from surgery is not known.

Authors: Lijun Wang, Fuxin Lin, Jun Wu, Yuming Jiao, Yong Cao, Yuanli Zhao and Shuo Wang

Altered regional homogeneity of prefrontal cortex in Parkinson’s disease with mild cognitive impairment

Mild cognitive impairment (MCI) is a common non-motor symptom of early Parkinson’s disease (PD), but the neural mechanisms underlying it remain poorly understood. The aim of the present study was to investigat...

Authors: De-Zhi Kang, Fu-Xiang Chen, Fu-Yong Chen, Ying Liu, Gang Wu, Liang-Hong Yu, Yuan-Xiang Lin and Zhang-Ya Lin

Astrocytoma simultaneously present with Meningioma-a report of two cases and review of the literature

This research paper will discuss the surgical management and possible mechanisms, as well as enlighten other features which can explain meningioma and astrocytoma simultaneously occurrences including statistic...

Authors: Aihemaiti Hasimu, Qiang Fu, Qingjiu Zhou, Shaoshan Li, Xiaofeng Zhu, Chen Liu, Dangmuren Jiafu Geng and Bo Liu

Traumatic lumbar spondylolisthesis without facet fracture at L4/L5. A case report and literature review

L4–L5 traumatic spondylolisthesis has been rarely reported in the literature. At lumbar spine level traumatic dislocation lesion realizes “traumatic spondylolisthesis or traumatic bilateral lumbar facet locked...

Authors: Dominique N’Dri-Oka, Souleymane Issa Sarki, Landry Konan and Yacouba Haro

Classification, mechanism and surgical treatments for spinal canal cysts

A variety of cystic lesions may develop in spinal canal. These cysts can be divided into intramedullary, intradural, extradural, cervical, thoracic, lumbar, and sacral cysts according to anatomical presentatio...

Authors: Jianjun Sun

Primary Inflammatory demyelinating pseudotumor in the left frontal lobe with meningeal involvement presenting as malignant neoplasms

Tumor-like demyelinating lesion is a rare form of IP, often indistinguishable from brain tumors on CT or MR imaging.

Authors: Yuyuan Ma, Hong Mou, Xueqiang Cai, Jie Ma and Gang Lu

Drug treatment of cerebral vasospasm after subarachnoid hemorrhage following aneurysms

Cerebral vasospasm (CVS) is a common and severe complication of aneurysmal subarachnoid hemorrhage (aSAH). Despite the improvement in treatment of aSAH, CVS complicating aSAH has remained the main cause of dea...

Authors: Yong-fei Liu, Han-Cheng Qiu, Juan Su and Wei-Jian Jiang

Chinese Neurosurgical Journal reviewer acknowledgement 2015

The editors of Chinese Neurosurgical Journal would like to thank all of our reviewers who have contributed to the journal in volume 1 (2015).

Authors: Jizong Zhao

Granulomatous hypophysitis: experience with eight surgical cases of a single center

Although primary hypophysitis is not uncommon, a granulomatous etiology of hypophysitis is relatively rare. Radiological and diagnostic characteristics of several isolated cases have been described to date. Ho...

Authors: Yan Xu, Lin Lou, Tian-Hua Wang, Yuan-Yuan Zhao, Xue-Xiang Cai, Jie Ma and Gang Lu

Primary spinal cord oligodendroglioma: a case report and review of the literature

Primary spinal cord oligodendroglioma is extremely rare. In an extensive review of this disease, 53 cases were reported. Furthermore, the authors summarize the characteristics of the primary spinal cord oligod...

Authors: Thara Tunthanathip and Thakul Oearsakul

Epidural spinal cord compression as initial clinical presentation of an acute myeloid leukaemia: case report and literature review

Epidural localization of myeloid leukaemia is rarely reported. Spinal cord compression as an initial presentation of acute myeloid leukaemia is extremely rare. This is a report of a 17-year-old black boy who p...

Authors: Dominique N’Dri Oka, Alpha Boubacar Bah, André Valentin Tokpa and Louis Derou

Success of linezolid therapy for postneurosurgical ventriculitis due to vancomycin-resistant Enterococcus faecium: case report and literature review

Vancomycin-resistant Enterococcus faecium ventriculitis is one of the most severe events in postneurosurgical intracranial infections. There are no guidelines recommending an appropriate treatment before.

Authors: Jia-Ji Qiu, Jie Tang and De-Ling Li

Neurosurgical publications in China: an analysis of the web of science database

Neurosurgery in China has made great progress. The aim of this study was to analyze neurosurgical publications by Chinese authors using the Web of Science database as a way to illustrate the current state of n...

Authors: Weiming Liu, Deling Li, Ming Ni, Wang Jia, Weiqing Wan, Jie Tang and Guijun Jia

Tailored keyhole surgery for basal ganglia cavernous malformation with preoperative three-dimensional pyramidal tracts assessment and intraoperative electrophysiological monitoring

Accurately mapping the pyramidal tracts preoperatively and intraoperatively is the primary concern when operating on cavernous malformations (CMS) in the basal ganglia. We have conducted new methods for preope...

Authors: Kai Quan, Geng Xu, Fan Zhao and Wei Zhu

Modified ventricular puncture combined with urokinase in the treatment of secondary intraventricular cast hemorrhage

We introduce a new catheter-based minimally invasive approach via frontal tuber for removing hypertensive intraventricular hemorrhage(IVH), and further compare its treatment efficacy with conventional external...

Authors: Jian Xu, Xia Liu, Ze-yu Wu, Xiao-dong Chen, Peng Lun, Yan Zhao, Bing Chen, Chang-qing Ding, Peng Sun and Yi-he Dou

Coexistent of paradoxical herniation and subdural hygroma: a case report

Coexistent of paradoxical herniation and subdural hygroma (SDG) is very rare, confusing symptoms may mislead the therapies.

Authors: Yi Feng and Yuhai Wang

One case of choriocarcinoma sellar region metastasis and literature review

Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization. Early erosion releases cancerous cells into the circulation to ...

Authors: Jin Sun and Yanlin Huang

Intraoperative rupture of blood blister-like aneurysm: a case report and review of literature

Blood blister-like aneurysms (BBLAs) are aneurysms from the non-branching sites of the internal carotid artery (ICA). Though rare lesions, they pose a high risk of intraoperative aneurysmal rupture. Definite t...

Authors: Roodrajeetsing Gopaul, Wen Shao Xiao, Jun Yan and Dang Zong Wei

Involvement of the visual pathway is not a risk factor of visual field deficits in patients with occipital arteriovenous malformations: an fMRI study

Occipital arteriovenous malformations (AVMs) are still one of neurosurgery’s most intriguing and challenging pathologies. In this study, we reviewed our series of patients with occipital AVMs admitted in Beiji...

Authors: Xianzeng Tong, Jun Wu, Fuxin Lin, Yong Cao, Yuanli Zhao, Zhen Jin and Shuo Wang

The analysis to the latest changes in NCCN Guidelines of Central Nervous System Cancers about low-grade gliomas and glioblastoma

Gliomas are the most common primary tumors of the central nervous system, around 70 % of the malignant brain tumors are gliomas. In the NCCN Guideline Ver.1 2015, the assessment before systemic treatment, trea...

Authors: Tianyu Wang, Xiong Xiao and Nan Ji

Different body mass index grade on the risk of developing glioma: a meta-analysis

Previous studies reported conflicting results about the risk of developing glioma and different body mass index. So we decided to execute a meta-analysis to solve the dispute.

Authors: Zi-Feng Dai, Qi-Lin Huang and Hai-Peng Liu

Schwannoma of the 6th nerve: case report and review of the literature

Schwannomas of the 6th nerve are extremely rare.Only 22 cases of intracranial schwannomas of the 6th cranial nerve pathologically confirmed have been reported.

Authors: Xin Li, Jingjun Li, Jing Li and Zhen Wu

Percutaneous balloon compression for primary trigeminal neuralgia in patients older than 80 years

It has been demonstrated that the incidence of trigeminal neuralgia in elderly patients is higher and thus, neurosurgeons often encounter elderly patients with this disorder. However, for those with poor basic...

Authors: Yuan-Feng Du, Qiao Gu, Ding-Bo Yang, Xiao-Qiao Dong, Quan Du, Hao Wang and Wen-Hua Yu

Cervical instability in Klippel-Feil syndrome: case report and review of the literature

The authors present a case of cervical myelopathy and radiculopathy in the setting of multiple Klippel-Feil syndrome abnormalities treated surgically with a single-level C3–C4 anterior cervical discectomy and ...

Authors: Aaron Wessell, Peter DeRosa, Abraham Cherrick and Jonathan H. Sherman

The historical change of brainstem glioma diagnosis and treatment: from imaging to molecular pathology and then molecular imaging

Understanding a process from shallow to deep is necessary for controlling and even curing diseases. The history of diagnosis and treatment of brainstem gliomas vividly reflects this process. The development of...

Authors: Liwei Zhang, Chang-cun Pan and Deling Li