HOXC8: a predictive glioma biomarker that induces epithelia-mesenchymal transition

Table 1 Univariate and multivariate Cox analysis in CGGA glioma samples

Clinical factors	Univariate			P	Multivariate			P
	HR	95%CI			HR	95%CI
	HR	Lower	Upper		HR	Lower	Upper
Age at diagnosis	1.044	1.026	1.062	< 0.0001	1.011	0.993	1.029	0.240
Gender (male)	1.162	0.792	1.704	0.443
IDH1 status (mutation)	0.335	0.219	0.511	< 0.0001	0.932	0.544	1.597	0.799
High HOXC8 expression	1.545	1.397	1.709	< 0.0001	1.247	1.110	1.402	< 0.0001
Grade (high grade)	3.960	2.960	5.299	< 0.0001	3.176	2.307	4.371	< 0.0001
TCGA subtype (mesenchymal type)	1.605	1.362	1.890	< 0.0001	1.048	0.866	1.267	0.631

IDH1: isocitrate dehydrogenase 1; CGGA: Chinese Glioma Genome Atlas; TCGA: The Cancer Genome Atlas; CI: Confidence Interval

ISSN: 2057-4967