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Table 1 Univariate and multivariate Cox analysis in CGGA glioma samples

From: HOXC8: a predictive glioma biomarker that induces epithelia-mesenchymal transition

Clinical factors Univariate P Multivariate P
HR 95%CI   HR 95%CI  
Lower Upper Lower Upper
Age at diagnosis 1.044 1.026 1.062 < 0.0001 1.011 0.993 1.029 0.240
Gender (male) 1.162 0.792 1.704 0.443     
IDH1 status (mutation) 0.335 0.219 0.511 < 0.0001 0.932 0.544 1.597 0.799
High HOXC8 expression 1.545 1.397 1.709 < 0.0001 1.247 1.110 1.402 < 0.0001
Grade (high grade) 3.960 2.960 5.299 < 0.0001 3.176 2.307 4.371 < 0.0001
TCGA subtype (mesenchymal type) 1.605 1.362 1.890 < 0.0001 1.048 0.866 1.267 0.631
  1. IDH1: isocitrate dehydrogenase 1; CGGA: Chinese Glioma Genome Atlas; TCGA: The Cancer Genome Atlas; CI: Confidence Interval