Fig. 2

BDNF via TrkB and PI3K/Akt pathway in the hippocampus suppresses autophagic flux and autophagosomes. mTORC1 phosphorylates Atg13 and inhibits Atg1, which is a necessary condition for suppressing autophagy
BDNF via TrkB and PI3K/Akt pathway in the hippocampus suppresses autophagic flux and autophagosomes. mTORC1 phosphorylates Atg13 and inhibits Atg1, which is a necessary condition for suppressing autophagy