Fig. 3From: ACSS2-related autophagy has a dual impact on memoryCBP has histone acetyltransferase (HAT) activity in which the metabolite acetyl-CoA is required for histone acetylation. ACSS2 maintains the level of localized histone acetylation by recapturing acetate from histone deacetylation to reform acetyl-CoA, providing substrates for HATBack to article page