Table 5 The pooled estimated rate of symptom relief and the incidence rate of complications in DAs- and surgery-treated patients
| Â | DAs | Surgery | ||||
|---|---|---|---|---|---|---|
Pooled result | Number of studies | Number of patients | Pooled result | Number of studies | Number of patients | |
Vision impairment improvement rate | 0.57 (0.38, 0.74) | 14 | 176 | 0.68 (0.51, 0.82) | 11 | 114 |
Headache improvement rate | 0.86 (0.72, 0.94) | 4 | 35 | 0.80 (0.32, 0.97) | 3 | 95 |
Menstrual disturbance improvement rate | 0.71 (0.16, 0.97) | 6 | 123 | 0.68 (0.62, 0.74) | 3 | 226 |
Galactorrhoea improvement rate | 0.89 (0.72, 0.96) | 6 | 29 | 0.33 (0.01, 0.94) | 3 | 176 |
Incidence rate of ACTH insufficiency | 0.10 (0.06, 0.16) | 9 | 286 | 0.25 (0.13, 0.43) | 11 | 387 |
Incidence rate of TSH deficiency | 0.19 (0.12, 0.28) | 7 | 194 | 0.24 (0.14, 0.38) | 12 | 475 |
Incidence rate of hypopituitarism | 0.29 (0.13, 0.54) | 4 | 99 | 0.17 (0.06, 0.38) | 11 | 709 |
Incidence rate of diabetes insipidus | NA | NA | NA | 0.17 (0.12, 0.25) | 27 | 1616 |