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Table 2 Demographic characteristics of the patients

From: The risk factors of hemorrhage in stereotactic needle biopsy for brain lesions in a large cohort: 10 years of experience in a single center

Variables

Hemorrhage

(N = 149, 4.66%)

Nonhemorrhage

(N = 3047, 95.34%)

p value

Diagnostic yield (%)

149 (100)

2789 (71.84)

 

Age (means ± standard)

50.72 ± 18.92

47.77 ± 18.22

0.055

Sex (%)

  

0.790

  Male

93 (62.42)

1936 (63.54)

 

  Female

56 (37.58)

1111 (36.46)

 

Location (%)

  

 < 0.001*

  Superficial

33 (22.15)

1825 (59.89)

 

  Deep-seated

116 (77.85)

1222 (40.11)

0.092

   Brainstem

21 (18.10)

313 (25.61)

 

   Other

95 (81.90)

909 (74.39)

 

Concomitant edema and enhancement on MR imaging (%)

  

0.009*

  Yes

85 (57.05)

1496 (49.10)

 

  No

64 (42.95)

1700 (50.90)

 

Enhancement on MR imaging alone (%)

  

0.220

  Yes

115 (77.18)

2047 (67.18)

 

  No

44 (22.82)

990 (32.82)

 

Hypertension (%)

  

0.538

  Yes

6 (4.03)

158 (5.19)

 

  No

143 (95.97)

2899 (94.81)

 

Intraoperative hypertension without a past history

  

0.036

  Yes

14 (9.40)

153 (5.02)

 

  No

135 (90.60)

2894 (94.98)

 

Antiplatelet treatment (%)

  

0.265

  Yes

8 (5.37)

111 (3.64)

 

  No

141 (94.63)

2936 (96.36)

 

Prolonged PT (%)

  

0.138

  Yes

10 (6.71)

127 (4.13)

 

  No

139 (93.29)

2947 (95.87)

 

Anesthesia (%)

  

0.871

  Local

140 (93.96)

2835 (93.04)

 

  General

9 (6.04)

212 (7.96)

 

Surgical method (%)

  

0.608

  Frame

102 (68.45)

2135 (70.06)

 

  Robot-assisted

28 (18.80)

484 (15.88)

 

  Navigation-assisted

19 (12.75)

428 (14.06)

 

Operator experience (%)

  

0.404

  Qualified neurosurgeons

67 (44.97)

1412 (46.34)

 

  Experienced neurosurgeons

82 (55.03)

1635 (53.66)

 

Histological grade of the lesion (%)

  

0.030*

  Benign

14 (9.40)

451 (14.80)

 

  Malignant

130 (87.25)

2381 (78.14)

 

  Uncertain

5 (3.35)

215 (7.06)

 

Pathology (%)

  

 < 0.001*

  High-grade glioma

95 (63.76)

1052 (34.53)

 

  Lymphoma

28 (16.78)

588 (19.30)

 

  Metastasis

2 (1.34)

99 (3.25)

 

  Nondiagnostic

5 (3.36)

253 (8.30)

 

  Others

19 (14.76)

1055 (34.62)

 
  1. PT, prothrombin time. Values are number (%) except where indicated otherwise. Special locations include the brainstem, sellar region and pineal region. Qualified neurosurgeons are those who successfully finished fewer than 200 stereotactic biopsies. Experienced neurosurgeons are those who successfully finished more than 200 stereotactic biopsies
  2. *Statistically significant difference