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Table 5 Risk factors associated with symptomatic hemorrhage

From: The risk factors of hemorrhage in stereotactic needle biopsy for brain lesions in a large cohort: 10 years of experience in a single center

Factor

Symptomatic hemorrhage

(n = 46)

Asymptomatic hemorrhage

(n = 103)

p value

Age (%)

50.19 ± 21.00

51.21 ± 18.32

0.802

Location of lesions (%)

   

  Superficial location

17 (36.96)

87(84.47)

 < 0.001*

  Deep-seated location

29 (63.04)

16(15.53)

 

  Brainstem

20 (68.96)

5(31.25)

0.027

  Other

9 (31.04)

11 (68.75)

 

Hemorrhage diameter

   

  5 ~ 50 mm

5 (10.87)

95 (92.23)

 < 0.001*

   > 50 mm

41 (89.13)

9 (7.77)

 

Hemorrhage extending pattern

   

  Restricted in trajectory

30 (65.22)

101 (98.06)

 < 0.001*

  Extension to ventricular or subarachnoid space

16 (34.78)

2 (1.94)

 

Concomitant edema and enhancement on MR imaging (%)

  

0.472

  Yes

30 (65.22)

60 (58.25)

 

  No

16 (34.78)

43 (41.75)

 

Histological grade (%)

  

0.991

  Benign

5 (10.87)

11 (10.68)

 

  Malignant

39 (84.78)

87 (84.47)

 

  Uncertain

2 (4.35)

5 (4.85)

 

Pathology (%)

  

0.773

  High-grade glioma

34 (73.90)

65 (63.11)

 

  Lymphoma

4 (8.70)

13 (12.62)

 

  Metastasis

4 (8.70)

11 (10.68)

 

  Nondiagnostic

2 (4.35)

6 (5.83)

 

  Others

2 (4.35)

8 (7.76)

 
  1. *Statistically significant