Fig. 4

Characteristics of tumors in the glioma transplantation models. Representative T2WI MRI images of glioma transplantation models at the 3rd week of the implantation of C6^WT cells (C6^WT group, n = 3), C6^TSP2+/+ cells (C6^TSP2+/+ group, n = 3), and C6^TSP2−/− cells (C6^TSP2−/− group, n = 3) in the cerebral cortex of rats (bar: 5 mm). The locations of the tumors are indicated by the dashed boxes. The volume analysis revealed a large tumor volume in the C6^TSP2+/+ group than that in the C6^WT group (P = 0.002), but they were not significantly different between the C6^TSP2−/− group and C6^WT group (P = 0.470)