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Fig. 2 | Chinese Neurosurgical Journal

Fig. 2

From: Transcriptomic analysis: the protection of over-expression thioredoxin reductase 1 in Parkinson’s disease

Fig. 2

Expression of TR1 and tyrosine hydroxylase (TH), oxidative damage, and total (up and down) differentially expressed mRNAs in Tg-A53T mice compared to TR1-A53T mice. A The expression of TR1 and TH is examined in the midbrain of the WT and Tg-A53T groups. B Relative expression of TR1 and TH. C The expression of TR1 and TH is examined in the midbrain in the Tg-A53T and TR1-A53T groups. D Relative expression of TR1 and TH. *p < 0.05, Tg-A53T vs. TR1-A53T group. E GSH, SOD, and MDA levels. F The bar indicates the p value (–log-transformed) the number of changed mRNAs in each pathway. The p value (Fisher p value) denotes the significance of the pathway correlated to the conditions. A lower p value (p value ≤ 0.05, considered statistically significant) denotes a more significant correlation

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Chinese Neurosurgical Journal

ISSN: 2057-4967

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