Roozenbeek B, Maas AI, Menon DK. Changing patterns in the epidemiology of traumatic brain injury. Nat Rev Neurol. 2013;9(4):231–6.
Article
PubMed
Google Scholar
Maas AI, Stocchetti N, Bullock R. Moderate and severe traumatic brain injury in adults. Lancet Neurol. 2008;7(8):728–41.
Article
PubMed
Google Scholar
Peterson, A.B., et al., Surveillance report of traumatic brain injury-related emergency department visits, hospitalizations, and deaths, United States, 2014. 2019.
Google Scholar
Tiret L, et al. The epidemiology of head trauma in Aquitaine (France), 1986: a community-based study of hospital admissions and deaths. Int J Epidemiol. 1990;19(1):133–40.
Article
CAS
PubMed
Google Scholar
Egea-Guerrero JJ, et al. S100B protein may detect brain death development after severe traumatic brain injury. J Neurotrauma. 2013;30(20):1762–9.
Article
PubMed
PubMed Central
Google Scholar
Leitgeb J, et al. Effects of gender on outcomes after traumatic brain injury. J Trauma. 2011;71(6):1620–6.
PubMed
Google Scholar
Hirschberg R, Weiss D, Zafonte R. Traumatic brain injury and gender: what is known and what is not; 2008.
Google Scholar
Wagner AK, et al. Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia. J Neurotrauma. 2004;21(2):125–36.
Article
PubMed
Google Scholar
Vagnerova K, Koerner IP, Hurn PD. Gender and the injured brain. Anesth Analg. 2008;107(1):201–14.
Article
PubMed
PubMed Central
Google Scholar
Bodhankar S, et al. Role for microglia in sex differences after ischemic stroke: importance of M2. Metab Brain Dis. 2015;30(6):1515–29.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shahrokhi N, et al. Effect of sex steroid hormones on brain edema, intracranial pressure, and neurologic outcomes after traumatic brain injury. Can J Physiol Pharmacol. 2010;88(4):414–21.
Article
CAS
PubMed
Google Scholar
Sekido R. The potential role of SRY in epigenetic gene regulation during brain sexual differentiation in mammals. Adv Genet. 2014;86:135–65.
Article
CAS
PubMed
Google Scholar
Ho B, et al. X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells. Biol Sex Differ. 2018;9(1):10.
Article
PubMed
PubMed Central
CAS
Google Scholar
Dekaban AS. Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights. Ann Neurol. 1978;4(4):345–56.
Article
CAS
PubMed
Google Scholar
Witelson SF, Kigar DL. Sylvian fissure morphology and asymmetry in men and women: bilateral differences in relation to handedness in men. J Comp Neurol. 1992;323(3):326–40.
Article
CAS
PubMed
Google Scholar
Kulynych JJ, et al. Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of Heschl’s gyrus and the planum temporale. Cereb Cortex. 1994;4(2):107–18.
Article
CAS
PubMed
Google Scholar
Holloway RL, et al. Sexual dimorphism of the human corpus callosum from three independent samples: relative size of the corpus callosum. Am J Phys Anthropol. 1993;92(4):481–98.
Article
CAS
PubMed
Google Scholar
Benbow CP. Sex-differences in mathematical reasoning ability in intellectually talented preadolescents - their nature, effects, and possible causes. Behav Brain Sci. 1988;11(2):169–83.
Article
Google Scholar
Bayir H, et al. Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients. J Neurotrauma. 2004;21(1):1–8.
Article
PubMed
Google Scholar
Farace E, Alves WM. Do women fare worse: a metaanalysis of gender differences in traumatic brain injury outcome. J Neurosurg. 2000;93(4):539–45.
Article
CAS
PubMed
Google Scholar
Gan B, Lim J, Ng I. Outcome of moderate and severe traumatic brain injury amongst the elderly in Singapore. Ann Acad Med Singapore. 2004;33(1):63–7.
CAS
PubMed
Google Scholar
Kirkness CJ, et al. Is there a sex difference in the course following traumatic brain injury? Biol Res Nurs. 2004;5(4):299–310.
Article
PubMed
Google Scholar
Wagner AK, et al. Intentional traumatic brain injury: epidemiology, risk factors, and associations with injury severity and mortality. J Trauma Acute Care Surg. 2000;49(3):404–10.
Article
CAS
Google Scholar
Munivenkatappa A, et al. Traumatic brain injury: does gender influence outcomes? Int J Crit Illn Inj Sci. 2016;6(2):70.
Article
PubMed
PubMed Central
Google Scholar
Berry C, et al. The effect of gender on patients with moderate to severe head injuries. J Trauma Acute Care Surg. 2009;67(5):950–3.
Article
Google Scholar
Groswasser Z, Cohen M, Keren O. Female TBI patients recover better than males. Brain Inj. 1998;12(9):805–8.
Article
CAS
PubMed
Google Scholar
Niemeier JP, et al. Gender differences in executive functions following traumatic brain injury. Neuropsychol Rehabil. 2007;17(3):293–313.
Article
PubMed
Google Scholar
Saban KL, et al. Sex differences in perceived life satisfaction and functional status one year after severe traumatic brain injury. J Women's Health. 2011;20(2):179–86.
Article
Google Scholar
Sarkaki AR, et al. Time-and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury. J Neurotrauma. 2013;30(1):47–54.
Article
PubMed
Google Scholar
Schmidt AT, et al. Decision making after pediatric traumatic brain injury: trajectory of recovery and relationship to age and gender. Int J Dev Neurosci. 2012;30(3):225–30.
Article
PubMed
Google Scholar
Ley EJ, et al. Gender impacts mortality after traumatic brain injury in teenagers. J Trauma Acute Care Surg. 2013;75(4):682–6.
Article
PubMed
Google Scholar
Albrecht JS, et al. Sex differences in mortality following isolated traumatic brain injury among older adults. J Trauma Acute Care Surg. 2016;81(3):486–92.
Article
PubMed
PubMed Central
Google Scholar
Renner C, et al. The influence of gender on the injury severity, course and outcome of traumatic brain injury. Brain Inj. 2012;26(11):1360–71.
Article
PubMed
Google Scholar
Slewa-Younan S, et al. Sex differences in injury severity and outcome measures after traumatic brain injury1. Arch Phys Med Rehabil. 2004;85(3):376–9.
Article
PubMed
Google Scholar
Acaz-Fonseca E, et al. Sex differences in glia reactivity after cortical brain injury. Glia. 2015;63(11):1966–81.
Article
PubMed
Google Scholar
Colantonio A, et al. Gender differences in self reported long term outcomes following moderate to severe traumatic brain injury. BMC Neurol. 2010;10(1):102.
Article
PubMed
PubMed Central
Google Scholar
Coronado VG, et al. Surveillance for traumatic brain injury-related deaths; United States, 1997–2007. MMWR Surveill Summ. 2011;60(5):1–32.
PubMed
Google Scholar
Scott C, et al. A comparison of adult outcomes for males compared to females following pediatric traumatic brain injury. Neuropsychology. 2015;29(4):501.
Article
PubMed
Google Scholar
Centers for Disease Control and Prevention. Report to congress on traumatic brain injury in the United States: epidemiology and rehabilitation. National Center for Injury Prevention and Control; 2015. pp. 1–72.
Mollayeva T, Mollayeva S, Colantonio. Traumatic brain injury: sex, gender and intersecting vulnerabilities. Nat Rev Neurol. 2018;14(12):711–22.
Article
PubMed
Google Scholar
De Nicola AF. Steroid hormones and neuronal regeneration. Adv Neurol. 1993;59:199–206.
PubMed
Google Scholar
He J, et al. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp Neurol. 2004;189(2):404–12.
Article
CAS
PubMed
Google Scholar
Djebaili M, Hoffman SW, Stein DG. Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex. Neuroscience. 2004;123(2):349–59.
Article
CAS
PubMed
Google Scholar
Shear DA, et al. Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury. Exp Neurol. 2002;178(1):59–67.
Article
CAS
PubMed
Google Scholar
Hall ED, Gibson TR, Pavel KM. Lack of a gender difference in post-traumatic neurodegeneration in the mouse controlled cortical impact injury model. J Neurotrauma. 2005;22(6):669–79.
Article
PubMed
Google Scholar
Pooley AE, et al. Sex differences in the traumatic stress response: the role of adult gonadal hormones. Biol Sex Differ. 2018;9(1):32.
Article
PubMed
PubMed Central
CAS
Google Scholar
Roof RL, Hall ED. Estrogen-related gender difference in survival rate and cortical blood flow after impact-acceleration head injury in rats. J Neurotrauma. 2000;17(12):1155–69.
Article
CAS
PubMed
Google Scholar
Carswell HV, Dominiczak AF, Macrae IM. Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2000;278(1):H290–4.
Article
CAS
PubMed
Google Scholar
Sarkaki AR, et al. Time- and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury. J Neurotrauma. 2013;30(1):47–54.
Article
PubMed
Google Scholar
Morrison B III, et al. In vitro central nervous system models of mechanically induced trauma: a review. J Neurotrauma. 1998;15(11):911–28.
Article
PubMed
Google Scholar
Olsson T. Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis. Immunol Rev. 1995;144(1):245–68.
Article
CAS
PubMed
Google Scholar
Ross SA, et al. The presence of tumour necrosis factor in CSF and plasma after severe head injury. Br J Neurosurg. 1994;8(4):419–25.
Article
CAS
PubMed
Google Scholar
Lawrence CB, Allan SM, Rothwell NJ. Interleukin-1β and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat. Eur J Neurosci. 1998;10(3):1188–95.
Article
CAS
PubMed
Google Scholar
Lenzlinger PM, et al. The duality of the inflammatory response to traumatic brain injury. Mol Neurobiol. 2001;24(1–3):169–81.
CAS
PubMed
Google Scholar
Chiaretti A, et al. Nerve growth factor expression correlates with severity and outcome of traumatic brain injury in children. Eur J Paediatr Neurol. 2008;12(3):195–204.
Article
PubMed
Google Scholar
Kontos HA, et al. Cerebral arteriolar damage by arachidonic acid and prostaglandin G2. Science. 1980;209(4462):1242–5.
Article
CAS
PubMed
Google Scholar
Roof RL, Hoffman SW, Stein DG. Progesterone protects against lipid peroxidation following traumatic brain injury in rats. Mol Chem Neuropathol. 1997;31(1):1–11.
Article
CAS
PubMed
Google Scholar
Morrow JD, et al. Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci U S A. 1992;89(22):10721–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hall ED, Pazara KE, Linseman KL. Sex differences in postischemic neuronal necrosis in gerbils. J Cereb Blood Flow Metab. 1991;11(2):292–8.
Article
CAS
PubMed
Google Scholar
Bizzozero OA, et al. Elevated protein carbonylation in the brain white matter and gray matter of patients with multiple sclerosis. J Neurosci Res. 2005;81(5):687–95.
Article
CAS
PubMed
Google Scholar
Sultana R, Butterfield DA. Role of oxidative stress in the progression of Alzheimer’s disease. J Alzheimers Dis. 2010;19(1):341–53.
Article
PubMed
CAS
Google Scholar
Irwin RW, et al. Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology. 2008;149(6):3167–75.
Article
CAS
PubMed
PubMed Central
Google Scholar
Caplan HW, Cox CS, Bedi SS. Do microglia play a role in sex differences in TBI? J Neurosci Res. 2017;95(1–2):509–17.
Article
CAS
PubMed
Google Scholar
Harry GJ, Kraft AD. Neuroinflammation and microglia: considerations and approaches for neurotoxicity assessment. Expert Opin Drug Metab Toxicol. 2008;4(10):1265–77.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ransohoff RM, Perry VH. Microglial physiology: unique stimuli, specialized responses. Annu Rev Immunol. 2009;27:119–45.
Article
CAS
PubMed
Google Scholar
Kingham P, Cuzner M, Pocock J. Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A-induced microglial activation. J Neurochem. 1999;73(2):538–47.
Article
CAS
PubMed
Google Scholar
Polazzi E, Contestabile A. Reciprocal interactions between microglia and neurons: from survival to neuropathology. Rev Neurosci. 2002;13(3):221–42.
Article
PubMed
Google Scholar
Ginhoux F, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330(6005):841–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lenz KM, McCarthy MM. A starring role for microglia in brain sex differences. Neuroscientist. 2015;21(3):306–21.
Article
CAS
PubMed
Google Scholar
Schafer DP, et al. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron. 2012;74(4):691–705.
Article
CAS
PubMed
PubMed Central
Google Scholar
Schwarz JM, Sholar PW, Bilbo SD. Sex differences in microglial colonization of the developing rat brain. J Neurochem. 2012;120(6):948–63.
CAS
PubMed
PubMed Central
Google Scholar
McCarthy MM, Wright CL, Schwarz JM. New tricks by an old dogma: mechanisms of the organizational/activational hypothesis of steroid-mediated sexual differentiation of brain and behavior. Horm Behav. 2009;55(5):655–65.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lenz KM, et al. Microglia are essential to masculinization of brain and behavior. J Neurosci. 2013;33(7):2761–72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Davis EC, Popper P, Gorski RA. The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area. Brain Res. 1996;734(1–2):10–8.
Article
CAS
PubMed
Google Scholar
Villapol S, Loane DJ, Burns MP. Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia. 2017;65(9):1423–38.
Article
PubMed
PubMed Central
Google Scholar
Crain JM, Nikodemova M, Watters JJ. Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice. J Neurosci Res. 2013;91(9):1143–51.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen Y, et al. Targeting microglial activation in stroke therapy: pharmacological tools and gender effects. Curr Med Chem. 2014;21(19):2146–55.
Article
CAS
PubMed
PubMed Central
Google Scholar
Barreto G, et al. Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone. Eur J Neurosci. 2007;25(10):3039–46.
Article
PubMed
Google Scholar
Habib P, Beyer C. Regulation of brain microglia by female gonadal steroids. J Steroid Biochem Mol Biol. 2015;146:3–14.
Article
CAS
PubMed
Google Scholar
Crosson B, Haaland KY. Subcortical functions in cognition: toward a consensus. J Int Neuropsychol Soc. 2003;9(7):1027–30.
Article
Google Scholar
Donnemiller E, et al. Impaired dopaminergic neurotransmission in patients with traumatic brain injury: a SPECT study using 123I-beta-CIT and 123I-IBZM. Eur J Nucl Med. 2000;27:1410–4.
Article
CAS
PubMed
Google Scholar
Wagner AK, et al. Gender and environmental enrichment impact dopamine transporter expression after experimental traumatic brain injury. Exp Neurol. 2005;195(2):475–83.
Article
CAS
PubMed
Google Scholar
Brown JM, et al. Differential protection against MPTP or methamphetamine toxicity in dopamine neurons by deletion of ppN/OFQ expression. J Neurochem. 2006;98(2):495–505.
Article
CAS
PubMed
Google Scholar
Xu X, et al. Sex-related differences in striatal dopaminergic system after traumatic brain injury. Brain Res Bull. 2016;124:214–21.
Article
CAS
PubMed
Google Scholar
Kuppers E, et al. Estrogen: a multifunctional messenger to nigrostriatal dopaminergic neurons. J Neurocytol. 2000;29(5–6):375–85.
Article
CAS
PubMed
Google Scholar
Castner SA, Xiao L, Becker JB. Sex differences in striatal dopamine: in vivo microdialysis and behavioral studies. Brain Res. 1993;610(1):127–34.
Article
CAS
PubMed
Google Scholar
Morissette M, et al. Sex and estrous cycle variations of rat striatal dopamine uptake sites. Neuroendocrinology. 1993;58:16–22.
Article
CAS
PubMed
Google Scholar
Rivest R, et al. Brain dopamine transporter: gender differences and effect of chronic haloperidol. Brain Res. 1995;692:269–72.
Article
CAS
PubMed
Google Scholar
Lavalaye J, et al. Effect of age and gender on dopamine transporter imaging with [123I] FP-CIT SPET in healthy volunteers. Eur J Nucl Med. 2000;27:867–9.
Article
CAS
PubMed
Google Scholar
Caplan B, et al. A dopamine pathway gene risk score for cognitive recovery following traumatic brain injury: methodological considerations, preliminary findings, and interactions with sex. J Head Trauma Rehabil. 2016;31(5):E15–29.
Article
Google Scholar
Basso MR, et al. FORUM sex differences on the WMS-III: findings concerning verbal paired associates and faces. Clin Neuropsychol. 2000;14(2):231–5.
Article
CAS
PubMed
Google Scholar
Halari R, et al. Sex differences and individual differences in cognitive performance and their relationship to endogenous gonadal hormones and gonadotropins. Behav Neurosci. 2005;119(1):104.
Article
CAS
PubMed
Google Scholar
Janowsky JS, et al. The cognitive neuropsychology of sex hormones in men and women. Dev Neuropsychol. 1998;14(2–3):421–40.
Article
Google Scholar
Ryan LM, Warden DL. Post concussion syndrome. Int Rev Psychiatry. 2003;15(4):310–6.
Article
PubMed
Google Scholar
Schmidt NB, Koselka M. Gender differences in patients with panic disorder: evaluating cognitive mediation of phobic avoidance. Cogn Ther Res. 2000;24(5):533–50.
Article
Google Scholar
Albanese BJ, et al. Anxiety sensitivity mediates gender differences in post-concussive symptoms in a clinical sample. Psychiatry Res. 2017;252:242–6.
Article
PubMed
PubMed Central
Google Scholar
Taylor HG, et al. A prospective study of short-and long-term outcomes after traumatic brain injury in children: behavior and achievement. Neuropsychology. 2002;16(1):15.
Article
PubMed
Google Scholar
Donders J, Hoffman NM. Gender differences in learning and memory after pediatric traumatic brain injury. Neuropsychology. 2002;16(4):491–9.
Article
PubMed
Google Scholar
Donders J, Woodward HR. Gender as a moderator of memory after traumatic brain injury in children. J Head Trauma Rehabil. 2003;18(2):106–15.
Article
PubMed
Google Scholar
Duff MC, et al. Beyond utterances: distributed cognition as a framework for studying discourse in adults with acquired brain injury. Semin Speech Lang. 2012;33:44–54 NIH Public Access.
Article
PubMed
PubMed Central
Google Scholar
Späni CB, Braun DJ, Van Eldik LJ. Sex-related responses after traumatic brain injury: considerations for preclinical modeling. Front Neuroendocrinol. 2018;50:52–66.
Article
PubMed
PubMed Central
Google Scholar
Anderson V, et al. Social competence at 6 months following childhood traumatic brain injury. J Int Neuropsychol Soc. 2013;19(5):539–50.
Article
PubMed
Google Scholar
Jones CA, Turkstra LS. Selling the story: narratives and charisma in adults with TBI. Brain Inj. 2011;25(9):844–57.
Article
PubMed
PubMed Central
Google Scholar
Yeates KO, et al. Peer relationships of children with traumatic brain injury. J Int Neuropsychol Soc. 2013;19(5):518–27.
Article
PubMed
Google Scholar
Hartley LL, Levin HS. Linguistic deficits after closed head-injury - a current appraisal. Aphasiology. 1990;4(4):353–70.
Article
Google Scholar
Despins EH, et al. Sex-based differences in perceived pragmatic communication ability of adults with traumatic brain injury. Arch Phys Med Rehabil. 2016;97(2 Suppl):S26–32.
Article
PubMed
Google Scholar
Babbage DR, et al. Meta-analysis of facial affect recognition difficulties after traumatic brain injury. Neuropsychology. 2011;25(3):277–85.
Article
PubMed
Google Scholar
Rosenberg H, et al. Emotion perception after moderate–severe traumatic brain injury: the valence effect and the role of working memory, processing speed, and nonverbal reasoning. Neuropsychology. 2015;29(4):509.
Article
PubMed
Google Scholar
Green RE, Turner GR, Thompson WF. Deficits in facial emotion perception in adults with recent traumatic brain injury. Neuropsychologia. 2004;42(2):133–41.
Article
PubMed
Google Scholar
Weisenbach SL, et al. Reduced emotion processing efficiency in healthy males relative to females. Soc Cogn Affect Neurosci. 2014;9(3):316–25.
Article
PubMed
Google Scholar
Rigon A, et al. The female advantage: sex as a possible protective factor against emotion recognition impairment following traumatic brain injury. Cogn Affect Behav Neurosci. 2016;16(5):866–75.
Article
PubMed
PubMed Central
Google Scholar
Mychasiuk R, et al. Mean girls: sex differences in the effects of mild traumatic brain injury on the social dynamics of juvenile rat play behaviour. Behav Brain Res. 2014;259:284–91.
Article
CAS
PubMed
Google Scholar
Behl C, Holsboer F. The female sex hormone oestrogen as a neuroprotectant. Trends Pharmacol Sci. 1999;20(11):441–4.
Article
CAS
PubMed
Google Scholar
Frankfurt M. Gonadal steroids and neuronal plasticity. Studies in the adult rat hypothalamus. Ann N Y Acad Sci. 1994;743:45–59 discussion 59-60.
Article
CAS
PubMed
Google Scholar
Matsumoto A, Arai Y. Male-female difference in synaptic organization of the ventromedial nucleus of the hypothalamus in the rat. Neuroendocrinology. 1986;42(3):232–6.
Article
CAS
PubMed
Google Scholar
Smith SS. Estrogen administration increases neuronal responses to excitatory amino-acids as a long-term effect. Brain Res. 1989;503(2):354–7.
Article
CAS
PubMed
Google Scholar
Brown TJ, et al. Regional sex differences in cell nuclear estrogen-binding capacity in the rat hypothalamus and preoptic area. Endocrinology. 1988;123(4):1761–70.
Article
CAS
PubMed
Google Scholar
Stein DG. Brain damage, sex hormones and recovery: a new role for progesterone and estrogen? Trends Neurosci. 2001;24(7):386–91.
Article
CAS
PubMed
Google Scholar
Brotfain E, et al. Neuroprotection by estrogen and progesterone in traumatic brain injury and spinal cord injury. Curr Neuropharmacol. 2016;14(6):641–53.
Article
CAS
PubMed
PubMed Central
Google Scholar
Armstead WM, Vavilala MS. Adrenomedullin reduces gender-dependent loss of hypotensive cerebrovasodilation after newborn brain injury through activation of ATP-dependent K channels. J Cereb Blood Flow Metab. 2007;27(10):1702–9.
Article
CAS
PubMed
Google Scholar
Armstead WM, et al. Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK. Neurol Res. 2012;34(6):530–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Armstead WM, Riley J, Vavilala MS. K channel impairment determines sex and age differences in epinephrine-mediated outcomes after brain injury. J Neurosci Res. 2017;95(10):1917–26.
Article
CAS
PubMed
PubMed Central
Google Scholar
Armstead WM, Riley J, Vavilala MS. TBI sex dependently upregulates ET-1 to impair autoregulation, which is aggravated by phenylephrine in males but is abrogated in females. J Neurotrauma. 2012;29(7):1483–90.
Article
PubMed
PubMed Central
Google Scholar
Yamamoto M, et al. Neuroprotective effect of hypothermia on neuronal injury in diffuse traumatic brain injury coupled with hypoxia and hypotension. J Neurotrauma. 1999;16(6):487–500.
Article
CAS
PubMed
Google Scholar
Shiozaki T, Mild Hypothermia Study Group in Japan, et al. A multicenter prospective randomized controlled trial of the efficacy of mild hypothermia for severely head injured patients with low intracranial pressure. J Neurosurg. 2001;94(1):50–4.
Article
CAS
PubMed
Google Scholar
Clifton GL, et al. Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med. 2001;344(8):556–63.
Article
CAS
PubMed
Google Scholar
Suzuki T, Bramlett HM, Dietrich WD. The importance of gender on the beneficial effects of posttraumatic hypothermia. Exp Neurol. 2003;184(2):1017–26.
Article
PubMed
Google Scholar
Lyeth BG, et al. Hypothermia blunts acetylcholine increase in CSF of traumatically brain injured rats. Mol Chem Neuropathol. 1993;18(3):247–56.
Article
CAS
PubMed
Google Scholar
Davies A. Hypothermia improves outcome from traumatic brain injury. Crit Care Resusc. 2005;7(3):238.
CAS
PubMed
Google Scholar