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The use of biomaterials, such as hydrogels, as a scaffold to deliver cells and drugs is becoming increasingly common to treat neurological conditions, including stroke. With a limited intrinsic ability to rege...
Hemodynamic factors are considered to play an important role in the initiation and recurrence of cerebral aneurysms. However, hemodynamic characteristics leading to the recurrence of aneurysms is not well reco...
MicroRNA (miRNA) is a type of endogenous non-coding RNA that can regulate cell proliferation, differentiation, invasion, apoptosis and several other biological activities by specially inducing gene silencing, ...
A paper was published in a Chinese medical journal that suggested that the placing of an intact vascularized omental pedicle would increase cerebral blood flow and could decelerate the development of Alzheimer...
Stem cell therapy or “cell therapy” has been demonstrated to be a potent treatment intervention in animal models of acute ischemic stroke, and recently has been introduced as an experimental therapy in early p...
Decompressive craniectomy (DC) in traumatic brain injury (TBI) patients has been subject of debate for neurosurgeons since long time. Our goal in this study is to evaluate the quality of life of these patients...
Deep brain stimulation (DBS) surgery is usually performed with the patients located in a half-sitting position. Therefore, complications associated with such position accompany, such as venous air embolism (VA...
Ganglioneuroma is a rare benign tumor, which is usually located in the posterior mediastinum and retroperitoneum. Occasionally, it involves the paraspinal region with intraspinal extension and becomes dumbbell...
Hypothalamic hamartoma (HH) is a rare developmental malformation often characterized by gelastic seizures. Recent advances in treating HH have led to dramatic improvements. However, clinical protocol of HH is ...
Endonasal transphenoidal approach by neuroendoscopy has its own advantage, such as direct access, invasive, better visualization of the anterior communicating artery aneurysm and so on. The study is to provide...
Nocardial brain abscesses are associated with significant morbidity and mortality rates. The optimal management remains unclear.
Acute lymphoblastic leukemia is a rare hematological malignancy. Pure subdural hemorrhages in a patient with acute lymphoblastic leukemia patient are extremely rare.
The development of three-dimensional (3D) printing technology provides a new method for surgical treatment, but currently there are few reports on its application in the treatment of aneurysm. The aim of the p...
Ruptured aneurysms with a presentation of intracerebral hemorrhage (ICH) and/or intraventricular hemorrhage (IVH) without subarachnoid hemorrhage (SAH) are rarely reported. Issues on the clinical characteristi...
Supratentorial primitive neuroectodermal tumors (sPNET) are rarely occurred in adults. Only 39 cases have been reported in the past decade. The transformation from low grade to aggressive astrocytoma is well k...
Since the introduction of neuro-endoscopy by Walter Dandy and his colleagues in the early 1920's, several efforts has been made to improve this tool for treatment of hydrocephalus, brain tumors, arachnoid cyst...
Petroclival meningiomas (PCMs) are technically challenging lesions. Although the standard retrosigmoid approach is one of the most effective approaches, this route may have some limitations for the tumors exte...
Epilepsy surgery has been accepted as an effective treatment in drug-resistant focal epilepsy. However, the number of epilepsy neurosurgeons is not enough in China compared with the huge demand. The content of...
Cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) is a serious and significant health problem in the worldwide. There are still no effective therapies for treatment of CVS in patients suffering from...
To investigate therapeutic effect of surgery that removes an intracranial foreign body through the intracranial sagittal sinus with help of intraoperative navigation and intraoperative fluorescein angiography.
The original article was published in Chinese Neurosurgical Journal 2016 2:13
Spinal extradural arachnoid cyst is extremely rare. The longest SEACs that have been reported in previous studies involved no more than 5 spinal segments. This study presents a case of SEAC diagnosed from T9 t...
External lumbar drainage (ELD) has gained wide popularity in neurosurgical practice since its’ first introduction by F. Vourc’h in 1963. It manifests encouraging prospects in control of refractory intracranial...
Rosai-Dorfman disease (RDD) is an idiopathic histiocytic proliferative disorder characterized by sinus histiocytosis and massive lymphadenopathy. Extranodal and central nervous system (CNS) involvement is unus...
The Erratum to this article has been published in Chinese Neurosurgical Journal 2016 2:19
Giant colloid cysts (size > 3 cm) are very rare with only few reported cases in the literature.
Patients who have a cerebral arteriovenous malformation (cAVMs) in the motor cortex can have displaced function. The finding and its relationship to recovery from surgery is not known.
Mild cognitive impairment (MCI) is a common non-motor symptom of early Parkinson’s disease (PD), but the neural mechanisms underlying it remain poorly understood. The aim of the present study was to investigat...
This research paper will discuss the surgical management and possible mechanisms, as well as enlighten other features which can explain meningioma and astrocytoma simultaneously occurrences including statistic...
L4–L5 traumatic spondylolisthesis has been rarely reported in the literature. At lumbar spine level traumatic dislocation lesion realizes “traumatic spondylolisthesis or traumatic bilateral lumbar facet locked...
A variety of cystic lesions may develop in spinal canal. These cysts can be divided into intramedullary, intradural, extradural, cervical, thoracic, lumbar, and sacral cysts according to anatomical presentatio...
Tumor-like demyelinating lesion is a rare form of IP, often indistinguishable from brain tumors on CT or MR imaging.
Cerebral vasospasm (CVS) is a common and severe complication of aneurysmal subarachnoid hemorrhage (aSAH). Despite the improvement in treatment of aSAH, CVS complicating aSAH has remained the main cause of dea...
The editors of Chinese Neurosurgical Journal would like to thank all of our reviewers who have contributed to the journal in volume 1 (2015).
Although primary hypophysitis is not uncommon, a granulomatous etiology of hypophysitis is relatively rare. Radiological and diagnostic characteristics of several isolated cases have been described to date. Ho...
Primary spinal cord oligodendroglioma is extremely rare. In an extensive review of this disease, 53 cases were reported. Furthermore, the authors summarize the characteristics of the primary spinal cord oligod...
Epidural localization of myeloid leukaemia is rarely reported. Spinal cord compression as an initial presentation of acute myeloid leukaemia is extremely rare. This is a report of a 17-year-old black boy who p...
Vancomycin-resistant Enterococcus faecium ventriculitis is one of the most severe events in postneurosurgical intracranial infections. There are no guidelines recommending an appropriate treatment before.
Neurosurgery in China has made great progress. The aim of this study was to analyze neurosurgical publications by Chinese authors using the Web of Science database as a way to illustrate the current state of n...
Accurately mapping the pyramidal tracts preoperatively and intraoperatively is the primary concern when operating on cavernous malformations (CMS) in the basal ganglia. We have conducted new methods for preope...
We introduce a new catheter-based minimally invasive approach via frontal tuber for removing hypertensive intraventricular hemorrhage(IVH), and further compare its treatment efficacy with conventional external...
Coexistent of paradoxical herniation and subdural hygroma (SDG) is very rare, confusing symptoms may mislead the therapies.
Chorionic carcinoma is a highly malignant gynecological tumor, frequently originating from trophoblastic cells in the uterus after fertilization. Early erosion releases cancerous cells into the circulation to ...
Blood blister-like aneurysms (BBLAs) are aneurysms from the non-branching sites of the internal carotid artery (ICA). Though rare lesions, they pose a high risk of intraoperative aneurysmal rupture. Definite t...
Occipital arteriovenous malformations (AVMs) are still one of neurosurgery’s most intriguing and challenging pathologies. In this study, we reviewed our series of patients with occipital AVMs admitted in Beiji...
Gliomas are the most common primary tumors of the central nervous system, around 70 % of the malignant brain tumors are gliomas. In the NCCN Guideline Ver.1 2015, the assessment before systemic treatment, trea...
Previous studies reported conflicting results about the risk of developing glioma and different body mass index. So we decided to execute a meta-analysis to solve the dispute.
Schwannomas of the 6th nerve are extremely rare.Only 22 cases of intracranial schwannomas of the 6th cranial nerve pathologically confirmed have been reported.
It has been demonstrated that the incidence of trigeminal neuralgia in elderly patients is higher and thus, neurosurgeons often encounter elderly patients with this disorder. However, for those with poor basic...
The authors present a case of cervical myelopathy and radiculopathy in the setting of multiple Klippel-Feil syndrome abnormalities treated surgically with a single-level C3–C4 anterior cervical discectomy and ...
Understanding a process from shallow to deep is necessary for controlling and even curing diseases. The history of diagnosis and treatment of brainstem gliomas vividly reflects this process. The development of...
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